| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the tanespimycin-5203 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| ALOXE3 | arachidonate lipoxygenase 3 |
| BAG2 | BCL2-associated athanogene 2 |
| BBC3 | BCL2 binding component 3 |
| BIN1 | bridging integrator 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CACYBP | calcyclin binding protein |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CD6 | CD6 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLU | clusterin |
| CRY2 | cryptochrome circadian clock 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CUL7 | cullin 7 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DAGLA | diacylglycerol lipase, alpha |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFNB3 | ephrin-B3 |
| EHD2 | EH-domain containing 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| FGF18 | fibroblast growth factor 18 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFT27 | intraflagellar transport 27 |
| IRS2 | insulin receptor substrate 2 |
| JAG1 | jagged 1 |
| KLK6 | kallikrein-related peptidase 6 |
| LAT2 | linker for activation of T cells family, member 2 |
| LRRC61 | leucine rich repeat containing 61 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED16 | mediator complex subunit 16 |
| MICB | MHC class I polypeptide-related sequence B |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NOX1 | NADPH oxidase 1 |
| NPR3 | natriuretic peptide receptor 3 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PLA2G3 | phospholipase A2, group III |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PON3 | paraoxonase 3 |
| PRKD2 | protein kinase D2 |
| PRMT2 | protein arginine methyltransferase 2 |
| PRSS16 | protease, serine, 16 (thymus) |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TES | testin LIM domain protein |
| TMEM97 | transmembrane protein 97 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TSPYL4 | TSPY-like 4 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF10 | zinc finger protein 10 |
| ZNF155 | zinc finger protein 155 |
| ZNF165 | zinc finger protein 165 |
| ZNF222 | zinc finger protein 222 |
| ZNF227 | zinc finger protein 227 |
| ZNF235 | zinc finger protein 235 |
| ZNF329 | zinc finger protein 329 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BLM | Bloom syndrome, RecQ helicase-like |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCNT1 | cyclin T1 |
| CDK5 | cyclin-dependent kinase 5 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLDN9 | claudin 9 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CORO2A | coronin, actin binding protein, 2A |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR3 | early growth response 3 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERF | Ets2 repressor factor |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FKBP5 | FK506 binding protein 5 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR19 | G protein-coupled receptor 19 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL17RB | interleukin 17 receptor B |
| IRX5 | iroquois homeobox 5 |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| LOC390998 | ribosomal protein L10 pseudogene |
| METTL8 | methyltransferase like 8 |
| MICALL2 | MICAL-like 2 |
| MMP9 | matrix metallopeptidase 9 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKCD | protein kinase C, delta |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB27B | RAB27B, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIX1 | SIX homeobox 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SMAD7 | SMAD family member 7 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| SYTL2 | synaptotagmin-like 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TIPIN | TIMELESS interacting protein |
| TMEM180 | transmembrane protein 180 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| WDR4 | WD repeat domain 4 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF124 | zinc finger protein 124 |
| ZNF276 | zinc finger protein 276 |
| ZNF573 | zinc finger protein 573 |
| ZXDC | ZXD family zinc finger C |