| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-521 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABHD3 | abhydrolase domain containing 3 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGTR2 | angiotensin II receptor, type 2 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ARMC4 | armadillo repeat containing 4 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C6 | complement component 6 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CACYBP | calcyclin binding protein |
| CALR | calreticulin |
| CD5 | CD5 molecule |
| CD93 | CD93 molecule |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLIC5 | chloride intracellular channel 5 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTTN | cortactin |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOK5 | docking protein 5 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GLS | glutaminase |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GPR137 | G protein-coupled receptor 137 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H3G | histone cluster 1, H3g |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFI35 | interferon-induced protein 35 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IFNG | interferon, gamma |
| IL1RN | interleukin 1 receptor antagonist |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LRRC20 | leucine rich repeat containing 20 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAOA | monoamine oxidase A |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MCOLN3 | mucolipin 3 |
| MT1F | metallothionein 1F |
| MT1X | metallothionein 1X |
| MVK | mevalonate kinase |
| NXPH4 | neurexophilin 4 |
| PARVA | parvin, alpha |
| PCP4 | Purkinje cell protein 4 |
| PDCD6 | programmed cell death 6 |
| PHF8 | PHD finger protein 8 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRF1 | perforin 1 (pore forming protein) |
| RCAN1 | regulator of calcineurin 1 |
| RGS11 | regulator of G-protein signaling 11 |
| RGS2 | regulator of G-protein signaling 2 |
| S100A4 | S100 calcium binding protein A4 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC23IP | SEC23 interacting protein |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SPON1 | spondin 1, extracellular matrix protein |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| STIP1 | stress-induced phosphoprotein 1 |
| STMN4 | stathmin-like 4 |
| TCF3 | transcription factor 3 |
| TMEM53 | transmembrane protein 53 |
| TMF1 | TATA element modulatory factor 1 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRIM38 | tripartite motif containing 38 |
| TSPAN32 | tetraspanin 32 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZNF184 | zinc finger protein 184 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANKRD36B | ankyrin repeat domain 36B |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC85C | coiled-coil domain containing 85C |
| CCS | copper chaperone for superoxide dismutase |
| CDK20 | cyclin-dependent kinase 20 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN15 | claudin 15 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNTFR | ciliary neurotrophic factor receptor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DCP1A | decapping mRNA 1A |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DPEP1 | dipeptidase 1 (renal) |
| EFNA3 | ephrin-A3 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| EPS8L2 | EPS8-like 2 |
| EXOC3 | exocyst complex component 3 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXD1 | forkhead box D1 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GMIP | GEM interacting protein |
| HIST1H2AM | histone cluster 1, H2am |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL4R | interleukin 4 receptor |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KLF10 | Kruppel-like factor 10 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL25 | kelch-like family member 25 |
| KLHL28 | kelch-like family member 28 |
| LEMD3 | LEM domain containing 3 |
| LMTK1 | lemur tail kinase 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MALL | mal, T-cell differentiation protein-like |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N4BP3 | NEDD4 binding protein 3 |
| NDC80 | NDC80 kinetochore complex component |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PF4 | platelet factor 4 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRKCD | protein kinase C, delta |
| PTK6 | protein tyrosine kinase 6 |
| PUS1 | pseudouridylate synthase 1 |
| RASIP1 | Ras interacting protein 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RRP1 | ribosomal RNA processing 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 |
| SQRDL | sulfide quinone reductase-like (yeast) |
| STK39 | serine threonine kinase 39 |
| SURF2 | surfeit 2 |
| SYT2 | synaptotagmin II |
| TBC1D16 | TBC1 domain family, member 16 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TJP2 | tight junction protein 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRIM8 | tripartite motif containing 8 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTI1 | TELO2 interacting protein 1 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZXDC | ZXD family zinc finger C |
