| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-5215 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ABHD4 | abhydrolase domain containing 4 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| ATXN1 | ataxin 1 |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP4 | bone morphogenetic protein 4 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CA4 | carbonic anhydrase IV |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCDC81 | coiled-coil domain containing 81 |
| CCNG2 | cyclin G2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIDO1 | death inducer-obliterator 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOCK10 | dedicator of cytokinesis 10 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| FASTKD2 | FAST kinase domains 2 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HSF2 | heat shock transcription factor 2 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JAG1 | jagged 1 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT16 | keratin 16, type I |
| MBNL2 | muscleblind-like splicing regulator 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MICB | MHC class I polypeptide-related sequence B |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NF1 | neurofibromin 1 |
| NLRX1 | NLR family member X1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NPR3 | natriuretic peptide receptor 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSBPL1A | oxysterol binding protein-like 1A |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PGF | placental growth factor |
| PLCD1 | phospholipase C, delta 1 |
| PPID | peptidylprolyl isomerase D |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RAI2 | retinoic acid induced 2 |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SEC24D | SEC24 family member D |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STIP1 | stress-induced phosphoprotein 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TES | testin LIM domain protein |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM2 | tripartite motif containing 2 |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| VLDLR | very low density lipoprotein receptor |
| YY2 | YY2 transcription factor |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF10 | zinc finger protein 10 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF235 | zinc finger protein 235 |
| ZNF329 | zinc finger protein 329 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATF3 | activating transcription factor 3 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CBX7 | chromobox homolog 7 |
| CCDC88C | coiled-coil domain containing 88C |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFAP44 | cilia and flagella associated protein 44 |
| CHPF | chondroitin polymerizing factor |
| CISH | cytokine inducible SH2-containing protein |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLDN9 | claudin 9 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CUL9 | cullin 9 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGR3 | early growth response 3 |
| EPN3 | epsin 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EVPL | envoplakin |
| FAM155B | family with sequence similarity 155, member B |
| GPR19 | G protein-coupled receptor 19 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXC10 | homeobox C10 |
| HOXC13 | homeobox C13 |
| HS1BP3 | HCLS1 binding protein 3 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL17RB | interleukin 17 receptor B |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KLF10 | Kruppel-like factor 10 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAMA3 | laminin, alpha 3 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MICALL2 | MICAL-like 2 |
| MID1IP1 | MID1 interacting protein 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PRKCD | protein kinase C, delta |
| RBM14 | RNA binding motif protein 14 |
| RGS16 | regulator of G-protein signaling 16 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SIRT6 | sirtuin 6 |
| SIX1 | SIX homeobox 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMAD7 | SMAD family member 7 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| SPHK1 | sphingosine kinase 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SYTL2 | synaptotagmin-like 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TMEM120B | transmembrane protein 120B |
| TMEM159 | transmembrane protein 159 |
| TMEM180 | transmembrane protein 180 |
| TRAPPC12 | trafficking protein particle complex 12 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF205 | zinc finger protein 205 |
| ZNF446 | zinc finger protein 446 |
| ZNF580 | zinc finger protein 580 |
| ZNF669 | zinc finger protein 669 |
| ZNF692 | zinc finger protein 692 |
| ZXDC | ZXD family zinc finger C |