| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-5222 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| ANXA1 | annexin A1 |
| ARG2 | arginase 2 |
| ARMC4 | armadillo repeat containing 4 |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CACYBP | calcyclin binding protein |
| CCNG2 | cyclin G2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL19A1 | collagen, type XIX, alpha 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DUSP13 | dual specificity phosphatase 13 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| FASTKD2 | FAST kinase domains 2 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL6R | interleukin 6 receptor |
| IRS2 | insulin receptor substrate 2 |
| JAG1 | jagged 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF21B | kinesin family member 21B |
| KLK6 | kallikrein-related peptidase 6 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| METTL16 | methyltransferase like 16 |
| MICB | MHC class I polypeptide-related sequence B |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NF1 | neurofibromin 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAX2 | paired box 2 |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PYY | peptide YY |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAI2 | snail family zinc finger 2 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK17A | serine/threonine kinase 17a |
| TES | testin LIM domain protein |
| TMEM97 | transmembrane protein 97 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| VLDLR | very low density lipoprotein receptor |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF235 | zinc finger protein 235 |
| ZNF329 | zinc finger protein 329 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCDC88C | coiled-coil domain containing 88C |
| CD82 | CD82 molecule |
| CDC25A | cell division cycle 25A |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CORO1A | coronin, actin binding protein, 1A |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTAGE9 | CTAGE family, member 9 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EGR3 | early growth response 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| HOXC11 | homeobox C11 |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IQCG | IQ motif containing G |
| IRX5 | iroquois homeobox 5 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIAA0125 | KIAA0125 |
| KIZ | kizuna centrosomal protein |
| KLF10 | Kruppel-like factor 10 |
| KLHL28 | kelch-like family member 28 |
| MID1IP1 | MID1 interacting protein 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKCD | protein kinase C, delta |
| RGS16 | regulator of G-protein signaling 16 |
| RHOG | ras homolog family member G |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RRP1 | ribosomal RNA processing 1 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SKIL | SKI-like proto-oncogene |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SYTL2 | synaptotagmin-like 2 |
| TEX264 | testis expressed 264 |
| THOP1 | thimet oligopeptidase 1 |
| TMEM159 | transmembrane protein 159 |
| TMEM180 | transmembrane protein 180 |
| TNS2 | tensin 2 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF276 | zinc finger protein 276 |
| ZNF446 | zinc finger protein 446 |
| ZNF573 | zinc finger protein 573 |
| ZNF692 | zinc finger protein 692 |
