| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tanespimycin-5223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANXA1 | annexin A1 |
| ASPH | aspartate beta-hydroxylase |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CACYBP | calcyclin binding protein |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCDC186 | coiled-coil domain containing 186 |
| CCNG2 | cyclin G2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLU | clusterin |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EGF | epidermal growth factor |
| ERP44 | endoplasmic reticulum protein 44 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HBEGF | heparin-binding EGF-like growth factor |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HFE | hemochromatosis |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL6R | interleukin 6 receptor |
| IRS2 | insulin receptor substrate 2 |
| JAG1 | jagged 1 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KLHL25 | kelch-like family member 25 |
| KLK6 | kallikrein-related peptidase 6 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| MAP1B | microtubule-associated protein 1B |
| MICB | MHC class I polypeptide-related sequence B |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NOTCH4 | notch 4 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUP214 | nucleoporin 214kDa |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PLA2G3 | phospholipase A2, group III |
| POPDC3 | popeye domain containing 3 |
| PRKCE | protein kinase C, epsilon |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RUNDC3A | RUN domain containing 3A |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAI2 | snail family zinc finger 2 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TBX3 | T-box 3 |
| TES | testin LIM domain protein |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM2 | tripartite motif containing 2 |
| UNKL | unkempt family zinc finger-like |
| VLDLR | very low density lipoprotein receptor |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF10 | zinc finger protein 10 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF329 | zinc finger protein 329 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BYSL | bystin-like |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CENPO | centromere protein O |
| CENPT | centromere protein T |
| CFAP44 | cilia and flagella associated protein 44 |
| CLDN7 | claudin 7 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| EGR3 | early growth response 3 |
| EPN3 | epsin 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| EXOSC9 | exosome component 9 |
| FAAH | fatty acid amide hydrolase |
| FAM65A | family with sequence similarity 65, member A |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR19 | G protein-coupled receptor 19 |
| HOXC13 | homeobox C13 |
| HTRA2 | HtrA serine peptidase 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL17RB | interleukin 17 receptor B |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MMP9 | matrix metallopeptidase 9 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N4BP3 | NEDD4 binding protein 3 |
| NARFL | nuclear prelamin A recognition factor-like |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCDHA6 | protocadherin alpha 6 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PGBD5 | piggyBac transposable element derived 5 |
| PRKCD | protein kinase C, delta |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PUS1 | pseudouridylate synthase 1 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RECQL4 | RecQ protein-like 4 |
| RGS16 | regulator of G-protein signaling 16 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF25 | ring finger protein 25 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STBD1 | starch binding domain 1 |
| SYTL2 | synaptotagmin-like 2 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCHH | trichohyalin |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFRC | transferrin receptor |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIM45 | tripartite motif containing 45 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBQLN4 | ubiquilin 4 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VEGFC | vascular endothelial growth factor C |
| WDR91 | WD repeat domain 91 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZXDC | ZXD family zinc finger C |
