tanespimycin-5585 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the tanespimycin-5585 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADCY7 adenylate cyclase 7
AIM2 absent in melanoma 2
ALX4 ALX homeobox 4
BAG2 BCL2-associated athanogene 2
BIN1 bridging integrator 1
BST2 bone marrow stromal cell antigen 2
C1ORF54 chromosome 1 open reading frame 54
CCDC81 coiled-coil domain containing 81
CCNG2 cyclin G2
CD200 CD200 molecule
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL1A1 collagen, type I, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CST4 cystatin S
DBF4B DBF4 zinc finger B
DDIT4 DNA-damage-inducible transcript 4
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOCK10 dedicator of cytokinesis 10
DST dystonin
DUX1 double homeobox 1
EGF epidermal growth factor
ERO1LB ERO1-like beta (S. cerevisiae)
FAM46C family with sequence similarity 46, member C
FGFBP1 fibroblast growth factor binding protein 1
FH fumarate hydratase
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GEM GTP binding protein overexpressed in skeletal muscle
GK2 glycerol kinase 2
GLRX glutaredoxin (thioltransferase)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR27 G protein-coupled receptor 27
GRB10 growth factor receptor-bound protein 10
HIPK2 homeodomain interacting protein kinase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
IFI6 interferon, alpha-inducible protein 6
IFT27 intraflagellar transport 27
JAK3 Janus kinase 3
KRT16 keratin 16, type I
LIMD1 LIM domains containing 1
MAP1B microtubule-associated protein 1B
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MXD4 MAX dimerization protein 4
NAP1L2 nucleosome assembly protein 1-like 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
OLFM1 olfactomedin 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PGF placental growth factor
PIGR polymeric immunoglobulin receptor
POPDC3 popeye domain containing 3
PPID peptidylprolyl isomerase D
PRSS16 protease, serine, 16 (thymus)
RBM5 RNA binding motif protein 5
RFPL2 ret finger protein-like 2
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RUSC2 RUN and SH3 domain containing 2
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SYNDIG1 synapse differentiation inducing 1
SYNRG synergin, gamma
TADA3 transcriptional adaptor 3
TES testin LIM domain protein
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPMT thiopurine S-methyltransferase
TRIL TLR4 interactor with leucine-rich repeats
TRIM21 tripartite motif containing 21
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSPAN7 tetraspanin 7
ULBP2 UL16 binding protein 2
UNKL unkempt family zinc finger-like
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZEB1 zinc finger E-box binding homeobox 1
ZFP64 ZFP64 zinc finger protein
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF10 zinc finger protein 10
ZNF165 zinc finger protein 165
ZNF222 zinc finger protein 222
ZNF227 zinc finger protein 227
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALPK1 alpha-kinase 1
ANKRD36B ankyrin repeat domain 36B
APOD apolipoprotein D
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASTE1 asteroid homolog 1 (Drosophila)
ATP13A2 ATPase type 13A2
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
BIK BCL2-interacting killer (apoptosis-inducing)
C10ORF2 chromosome 10 open reading frame 2
C1ORF35 chromosome 1 open reading frame 35
C5AR2 complement component 5a receptor 2
CAMTA1 calmodulin binding transcription activator 1
CBX7 chromobox homolog 7
CD82 CD82 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN9 claudin 9
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CORO2A coronin, actin binding protein, 2A
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DENND4B DENN/MADD domain containing 4B
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
EXD3 exonuclease 3'-5' domain containing 3
FAM120C family with sequence similarity 120C
FAM155B family with sequence similarity 155, member B
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FZD4 frizzled class receptor 4
GPR19 G protein-coupled receptor 19
HIST1H4D histone cluster 1, H4d
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
ISYNA1 inositol-3-phosphate synthase 1
JUN jun proto-oncogene
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KLF10 Kruppel-like factor 10
KLF7 Kruppel-like factor 7 (ubiquitous)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MED15 mediator complex subunit 15
METTL4 methyltransferase like 4
MICALL2 MICAL-like 2
MID1IP1 MID1 interacting protein 1
MMP9 matrix metallopeptidase 9
MTCL1 microtubule crosslinking factor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBEAL2 neurobeachin-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OLFML2A olfactomedin-like 2A
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAQR6 progestin and adipoQ receptor family member VI
PELI1 pellino E3 ubiquitin protein ligase 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKCD protein kinase C, delta
PRSS8 protease, serine, 8
PTPRE protein tyrosine phosphatase, receptor type, E
PUS1 pseudouridylate synthase 1
RBM14 RNA binding motif protein 14
RBM15B RNA binding motif protein 15B
RBM38 RNA binding motif protein 38
RGS16 regulator of G-protein signaling 16
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RRAGC Ras-related GTP binding C
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCO2 SCO2 cytochrome c oxidase assembly protein
SH3GL1 SH3-domain GRB2-like 1
SHROOM2 shroom family member 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SMAD7 SMAD family member 7
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SUSD4 sushi domain containing 4
SYTL2 synaptotagmin-like 2
TCHH trichohyalin
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBIAD1 UbiA prenyltransferase domain containing 1
ULK1 unc-51 like autophagy activating kinase 1
USB1 U6 snRNA biogenesis 1
WRAP73 WD repeat containing, antisense to TP73
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF324 zinc finger protein 324
ZNF573 zinc finger protein 573
ZNF862 zinc finger protein 862