| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the tanespimycin-5586 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ADCY7 | adenylate cyclase 7 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| BST2 | bone marrow stromal cell antigen 2 |
| CA4 | carbonic anhydrase IV |
| CALCR | calcitonin receptor |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCA1 | chloride channel accessory 1 |
| CNN1 | calponin 1, basic, smooth muscle |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DBF4B | DBF4 zinc finger B |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EDNRA | endothelin receptor type A |
| EGF | epidermal growth factor |
| FAM46C | family with sequence similarity 46, member C |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| GGT1 | gamma-glutamyltransferase 1 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| HFE | hemochromatosis |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IL2RB | interleukin 2 receptor, beta |
| IL6R | interleukin 6 receptor |
| ING4 | inhibitor of growth family, member 4 |
| INSR | insulin receptor |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIFC3 | kinesin family member C3 |
| KLK12 | kallikrein-related peptidase 12 |
| LDB3 | LIM domain binding 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MPPE1 | metallophosphoesterase 1 |
| NMBR | neuromedin B receptor |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEG3 | paternally expressed 3 |
| PGF | placental growth factor |
| PLA2G3 | phospholipase A2, group III |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| POPDC3 | popeye domain containing 3 |
| PQBP1 | polyglutamine binding protein 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PXDC1 | PX domain containing 1 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RETN | resistin |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RPLP2 | ribosomal protein, large, P2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCARF1 | scavenger receptor class F, member 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH2D3A | SH2 domain containing 3A |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBX3 | T-box 3 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TRAC | T cell receptor alpha constant |
| TRD | T cell receptor delta locus |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBA3C | tubulin, alpha 3c |
| UPK1B | uroplakin 1B |
| YY2 | YY2 transcription factor |
| ZNF10 | zinc finger protein 10 |
| ZNF227 | zinc finger protein 227 |
| ZNF235 | zinc finger protein 235 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AXIN1 | axin 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNO | cyclin O |
| CD302 | CD302 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPT | centromere protein T |
| CFAP44 | cilia and flagella associated protein 44 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CUL9 | cullin 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DNMBP | dynamin binding protein |
| DUSP2 | dual specificity phosphatase 2 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGR3 | early growth response 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| F8 | coagulation factor VIII, procoagulant component |
| FBRS | fibrosin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR19 | G protein-coupled receptor 19 |
| HOXA4 | homeobox A4 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL17RB | interleukin 17 receptor B |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| METTL1 | methyltransferase like 1 |
| MNT | MAX network transcriptional repressor |
| MOAP1 | modulator of apoptosis 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MVD | mevalonate (diphospho) decarboxylase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NPY5R | neuropeptide Y receptor Y5 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PGBD5 | piggyBac transposable element derived 5 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRKCD | protein kinase C, delta |
| PUS1 | pseudouridylate synthase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RECQL4 | RecQ protein-like 4 |
| RGS16 | regulator of G-protein signaling 16 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SACS | sacsin molecular chaperone |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SHROOM2 | shroom family member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMAD7 | SMAD family member 7 |
| SYT17 | synaptotagmin XVII |
| SYTL2 | synaptotagmin-like 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM62 | transmembrane protein 62 |
| TRIB1 | tribbles pseudokinase 1 |
| TRMT61B | tRNA methyltransferase 61B |
| USB1 | U6 snRNA biogenesis 1 |
| VGF | VGF nerve growth factor inducible |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF286A | zinc finger protein 286A |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
| ZXDC | ZXD family zinc finger C |