| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tanespimycin-5914 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CACYBP | calcyclin binding protein |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC81 | coiled-coil domain containing 81 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCNG2 | cyclin G2 |
| CD300A | CD300a molecule |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLSTN3 | calsyntenin 3 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DIDO1 | death inducer-obliterator 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DTNB | dystrobrevin, beta |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFNA3 | ephrin-A3 |
| EGF | epidermal growth factor |
| EWSR1 | EWS RNA-binding protein 1 |
| EXOC6B | exocyst complex component 6B |
| F2R | coagulation factor II (thrombin) receptor |
| FAM110B | family with sequence similarity 110, member B |
| FCMR | Fc fragment of IgM receptor |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR2 | fibroblast growth factor receptor 2 |
| FH | fumarate hydratase |
| FLJ42627 | uncharacterized LOC645644 |
| FUS | FUS RNA binding protein |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLP1R | glucagon-like peptide 1 receptor |
| GM2A | GM2 ganglioside activator |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXA1 | homeobox A1 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGL | immunoglobulin lambda locus |
| ING4 | inhibitor of growth family, member 4 |
| LMNA | lamin A/C |
| MAP1B | microtubule-associated protein 1B |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MCL1 | myeloid cell leukemia 1 |
| MED16 | mediator complex subunit 16 |
| MSMB | microseminoprotein, beta- |
| MXD4 | MAX dimerization protein 4 |
| NUP54 | nucleoporin 54kDa |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PARVA | parvin, alpha |
| PGF | placental growth factor |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REST | RE1-silencing transcription factor |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF39 | ring finger protein 39 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIRPA | signal-regulatory protein alpha |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD4 | SMAD family member 4 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SSPN | sarcospan |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TCTN2 | tectonic family member 2 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TNS1 | tensin 1 |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC2 | tuberous sclerosis 2 |
| TSPAN9 | tetraspanin 9 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| UNKL | unkempt family zinc finger-like |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VGF | VGF nerve growth factor inducible |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF329 | zinc finger protein 329 |
| ZNF43 | zinc finger protein 43 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADRA2B | adrenoceptor alpha 2B |
| AFAP1 | actin filament associated protein 1 |
| ALS2CL | ALS2 C-terminal like |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5AR1 | complement component 5a receptor 1 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CD8A | CD8a molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CORO7 | coronin 7 |
| CORT | cortistatin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DEPDC5 | DEP domain containing 5 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| EGFL7 | EGF-like-domain, multiple 7 |
| EGR3 | early growth response 3 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ETV4 | ets variant 4 |
| FADS2 | fatty acid desaturase 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGF22 | fibroblast growth factor 22 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXC1 | forkhead box C1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR19 | G protein-coupled receptor 19 |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3I | histone cluster 1, H3i |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA4 | homeobox A4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IQCE | IQ motif containing E |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1456 | KIAA1456 |
| KLF10 | Kruppel-like factor 10 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KPTN | kaptin (actin binding protein) |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| MEGF8 | multiple EGF-like-domains 8 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPFFR1 | neuropeptide FF receptor 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PALM | paralemmin |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PENK | proenkephalin |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| POMT2 | protein-O-mannosyltransferase 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PRAMEF11 | PRAME family member 11 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRR34 | proline rich 34 |
| RAB3D | RAB3D, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RRAGB | Ras-related GTP binding B |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SMAD7 | SMAD family member 7 |
| SPATA2L | spermatogenesis associated 2-like |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TAOK1 | TAO kinase 1 |
| TFF2 | trefoil factor 2 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNS2 | tensin 2 |
| TOR4A | torsin family 4, member A |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZNF250 | zinc finger protein 250 |
| ZNF286A | zinc finger protein 286A |
| ZNF365 | zinc finger protein 365 |
| ZPR1 | ZPR1 zinc finger |
| ZXDC | ZXD family zinc finger C |
