| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-5953 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ADCY7 | adenylate cyclase 7 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARL4C | ADP-ribosylation factor-like 4C |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CA4 | carbonic anhydrase IV |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC81 | coiled-coil domain containing 81 |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CD8A | CD8a molecule |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CPA4 | carboxypeptidase A4 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DBF4B | DBF4 zinc finger B |
| DIDO1 | death inducer-obliterator 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP13 | dual specificity phosphatase 13 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FGFR2 | fibroblast growth factor receptor 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GIMAP5 | GTPase, IMAP family member 5 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPR87 | G protein-coupled receptor 87 |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| HOXA1 | homeobox A1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGA6 | integrin, alpha 6 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MAP1B | microtubule-associated protein 1B |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NGDN | neuroguidin, EIF4E binding protein |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHB13 | protocadherin beta 13 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PGF | placental growth factor |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POLL | polymerase (DNA directed), lambda |
| POPDC3 | popeye domain containing 3 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| QKI | QKI, KH domain containing, RNA binding |
| RANBP1 | RAN binding protein 1 |
| RBM5 | RNA binding motif protein 5 |
| RFPL2 | ret finger protein-like 2 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPL7 | ribosomal protein L7 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRCAP | Snf2-related CREBBP activator protein |
| SSPN | sarcospan |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STIP1 | stress-induced phosphoprotein 1 |
| STK17B | serine/threonine kinase 17b |
| TBC1D5 | TBC1 domain family, member 5 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TXNIP | thioredoxin interacting protein |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| ULBP2 | UL16 binding protein 2 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF224 | zinc finger protein 224 |
| ZNF227 | zinc finger protein 227 |
| ZNF235 | zinc finger protein 235 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADAMTSL4 | ADAMTS-like 4 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AHSP | alpha hemoglobin stabilizing protein |
| AMH | anti-Mullerian hormone |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARMC4 | armadillo repeat containing 4 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASIC2 | acid sensing (proton gated) ion channel 2 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| CALML5 | calmodulin-like 5 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCDC71 | coiled-coil domain containing 71 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNO | cyclin O |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD70 | CD70 molecule |
| CERS4 | ceramide synthase 4 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFD | complement factor D (adipsin) |
| CISH | cytokine inducible SH2-containing protein |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COLEC11 | collectin sub-family member 11 |
| DUSP2 | dual specificity phosphatase 2 |
| ECEL1 | endothelin converting enzyme-like 1 |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| EN2 | engrailed homeobox 2 |
| FGF13 | fibroblast growth factor 13 |
| FOXN2 | forkhead box N2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR19 | G protein-coupled receptor 19 |
| GPR21 | G protein-coupled receptor 21 |
| HIST1H1T | histone cluster 1, H1t |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| JMJD4 | jumonji domain containing 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIF13A | kinesin family member 13A |
| KLF10 | Kruppel-like factor 10 |
| LHX3 | LIM homeobox 3 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MC3R | melanocortin 3 receptor |
| MEFV | Mediterranean fever |
| MTCL1 | microtubule crosslinking factor 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME5 | NME/NM23 family member 5 |
| NOTCH4 | notch 4 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPPB | natriuretic peptide B |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTF3 | neurotrophin 3 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PALM | paralemmin |
| PLTP | phospholipid transfer protein |
| PRM1 | protamine 1 |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| RAB30 | RAB30, member RAS oncogene family |
| RGS16 | regulator of G-protein signaling 16 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RORC | RAR-related orphan receptor C |
| S100A9 | S100 calcium binding protein A9 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNTA1 | syntrophin, alpha 1 |
| SPATA2L | spermatogenesis associated 2-like |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TOM1 | target of myb1 (chicken) |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF286A | zinc finger protein 286A |
| ZNF358 | zinc finger protein 358 |
