| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tanespimycin-6166 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACVR1B | activin A receptor, type IB |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| ADRA2C | adrenoceptor alpha 2C |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AQP9 | aquaporin 9 |
| BAG3 | BCL2-associated athanogene 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BCL2L1 | BCL2-like 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLTA | clathrin, light chain A |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL4A2 | collagen, type IV, alpha 2 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EML2 | echinoderm microtubule associated protein like 2 |
| FAM13A | family with sequence similarity 13, member A |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAS | Fas cell surface death receptor |
| FCGBP | Fc fragment of IgG binding protein |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| GPR153 | G protein-coupled receptor 153 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXA7 | homeobox A7 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL7R | interleukin 7 receptor |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KLHL36 | kelch-like family member 36 |
| MAGEB4 | melanoma antigen family B4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MNMIP1 | manchette microtubule inner protein 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MST1L | macrophage stimulating 1-like |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NNAT | neuronatin |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PERP | PERP, TP53 apoptosis effector |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIGR | polymeric immunoglobulin receptor |
| PIR | pirin (iron-binding nuclear protein) |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PMP22 | peripheral myelin protein 22 |
| PPID | peptidylprolyl isomerase D |
| PRDM10 | PR domain containing 10 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| REC8 | REC8 meiotic recombination protein |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STAC | SH3 and cysteine rich domain |
| TEF | thyrotrophic embryonic factor |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS1 | thrombospondin 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRD | T cell receptor delta locus |
| TRIM23 | tripartite motif containing 23 |
| TSC2 | tuberous sclerosis 2 |
| WSCD1 | WSC domain containing 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AEN | apoptosis enhancing nuclease |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ARRB1 | arrestin, beta 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCDC86 | coiled-coil domain containing 86 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENDOG | endonuclease G |
| EXOSC5 | exosome component 5 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IRX5 | iroquois homeobox 5 |
| KIF21B | kinesin family member 21B |
| KLK5 | kallikrein-related peptidase 5 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MEGF8 | multiple EGF-like-domains 8 |
| METTL8 | methyltransferase like 8 |
| MNT | MAX network transcriptional repressor |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOP2 | NOP2 nucleolar protein |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PDZD7 | PDZ domain containing 7 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RABEPK | Rab9 effector protein with kelch motifs |
| REEP4 | receptor accessory protein 4 |
| RETN | resistin |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RFXAP | regulatory factor X-associated protein |
| RGS16 | regulator of G-protein signaling 16 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SMAD7 | SMAD family member 7 |
| STC2 | stanniocalcin 2 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STRA13 | stimulated by retinoic acid 13 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCTA | T-cell leukemia translocation altered |
| TERT | telomerase reverse transcriptase |
| TFB2M | transcription factor B2, mitochondrial |
| THEM6 | thioesterase superfamily member 6 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM110 | transmembrane protein 110 |
| TNF | tumor necrosis factor |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIB3 | tribbles pseudokinase 3 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TXLNG | taxilin gamma |
| UNG | uracil-DNA glycosylase |
| USB1 | U6 snRNA biogenesis 1 |
| WDR3 | WD repeat domain 3 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
