| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the tanespimycin-6177 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ANXA1 | annexin A1 |
| ANXA6 | annexin A6 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BAG3 | BCL2-associated athanogene 3 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CACYBP | calcyclin binding protein |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) |
| CD163 | CD163 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLK1 | CDC-like kinase 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EED | embryonic ectoderm development |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGF6 | fibroblast growth factor 6 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IL1R1 | interleukin 1 receptor, type I |
| IL7R | interleukin 7 receptor |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA1109 | KIAA1109 |
| KIF24 | kinesin family member 24 |
| KYNU | kynureninase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MFAP2 | microfibrillar-associated protein 2 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MSRB2 | methionine sulfoxide reductase B2 |
| MST1L | macrophage stimulating 1-like |
| MT1HL1 | metallothionein 1H-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAX5 | paired box 5 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHACTR1 | phosphatase and actin regulator 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPID | peptidylprolyl isomerase D |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPAG5 | sperm associated antigen 5 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STIP1 | stress-induced phosphoprotein 1 |
| STON1 | stonin 1 |
| THBS1 | thrombospondin 1 |
| TM2D1 | TM2 domain containing 1 |
| TPM1 | tropomyosin 1 (alpha) |
| WAPAL | wings apart-like homolog (Drosophila) |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AEN | apoptosis enhancing nuclease |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALPK1 | alpha-kinase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARRB1 | arrestin, beta 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CD1D | CD1d molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DFNA5 | deafness, autosomal dominant 5 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENAH | enabled homolog (Drosophila) |
| ENDOG | endonuclease G |
| FAM127B | family with sequence similarity 127, member B |
| FAM131A | family with sequence similarity 131, member A |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FOSL1 | FOS-like antigen 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD1 | FERM domain containing 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HIRA | histone cell cycle regulator |
| HIST1H1T | histone cluster 1, H1t |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| KIF21B | kinesin family member 21B |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| METTL1 | methyltransferase like 1 |
| METTL8 | methyltransferase like 8 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MTA2 | metastasis associated 1 family, member 2 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDZD7 | PDZ domain containing 7 |
| PFN2 | profilin 2 |
| POLL | polymerase (DNA directed), lambda |
| PQLC2 | PQ loop repeat containing 2 |
| PRAMEF11 | PRAME family member 11 |
| PRDM13 | PR domain containing 13 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RFXAP | regulatory factor X-associated protein |
| RGS16 | regulator of G-protein signaling 16 |
| RIN1 | Ras and Rab interactor 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SETD6 | SET domain containing 6 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| TCTA | T-cell leukemia translocation altered |
| TEP1 | telomerase-associated protein 1 |
| TEX40 | testis expressed 40 |
| TNF | tumor necrosis factor |
| TRAF1 | TNF receptor-associated factor 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TXLNG | taxilin gamma |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF324 | zinc finger protein 324 |
