| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-6184 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACAN | aggrecan |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AIM1L | absent in melanoma 1-like |
| ANXA6 | annexin A6 |
| BAG3 | BCL2-associated athanogene 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C8B | complement component 8, beta polypeptide |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CAT | catalase |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNG2 | cyclin G2 |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP41 | centrosomal protein 41kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| COL2A1 | collagen, type II, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM107A | family with sequence similarity 107, member A |
| FAS | Fas cell surface death receptor |
| FCAR | Fc fragment of IgA receptor |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| GAMT | guanidinoacetate N-methyltransferase |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HRH1 | histamine receptor H1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| JMJD6 | jumonji domain containing 6 |
| KIAA1109 | KIAA1109 |
| KLHL35 | kelch-like family member 35 |
| KLK6 | kallikrein-related peptidase 6 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MED25 | mediator complex subunit 25 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRC2 | mannose receptor, C type 2 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MST1L | macrophage stimulating 1-like |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE8B | phosphodiesterase 8B |
| PPID | peptidylprolyl isomerase D |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERHL2 | serine hydrolase-like 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SFTPB | surfactant protein B |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SMIM14 | small integral membrane protein 14 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPTA1 | spectrin, alpha, erythrocytic 1 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STATH | statherin |
| STIP1 | stress-induced phosphoprotein 1 |
| SV2B | synaptic vesicle glycoprotein 2B |
| THBS1 | thrombospondin 1 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADRB2 | adrenoceptor beta 2, surface |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AEN | apoptosis enhancing nuclease |
| ARSB | arylsulfatase B |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CAPN15 | calpain 15 |
| CCDC86 | coiled-coil domain containing 86 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD69 | CD69 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFAP44 | cilia and flagella associated protein 44 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CPNE7 | copine VII |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP2 | dual specificity phosphatase 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR1 | early growth response 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EVA1B | eva-1 homolog B (C. elegans) |
| FAM57A | family with sequence similarity 57, member A |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FHIT | fragile histidine triad |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GCH1 | GTP cyclohydrolase 1 |
| GLCE | glucuronic acid epimerase |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H1T | histone cluster 1, H1t |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| INHBE | inhibin, beta E |
| KIF21B | kinesin family member 21B |
| KLK5 | kallikrein-related peptidase 5 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| METTL21B | methyltransferase like 21B |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPI | mannose phosphate isomerase |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCS1 | neuronal calcium sensor 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| PUS1 | pseudouridylate synthase 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCRIB | scribbled planar cell polarity protein |
| SETD6 | SET domain containing 6 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SMAD7 | SMAD family member 7 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIDR | scaffolding protein involved in DNA repair |
| STC2 | stanniocalcin 2 |
| STRA13 | stimulated by retinoic acid 13 |
| SURF2 | surfeit 2 |
| TERT | telomerase reverse transcriptase |
| THEM6 | thioesterase superfamily member 6 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM177 | transmembrane protein 177 |
| TNF | tumor necrosis factor |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRIB3 | tribbles pseudokinase 3 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UNG | uracil-DNA glycosylase |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT2 | xylosyltransferase II |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
