| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-6185 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHI1 | Abelson helper integration site 1 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASTN2 | astrotactin 2 |
| BAG3 | BCL2-associated athanogene 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CCNK | cyclin K |
| CD300A | CD300a molecule |
| CD70 | CD70 molecule |
| CDC14A | cell division cycle 14A |
| CDC14B | cell division cycle 14B |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CEP135 | centrosomal protein 135kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL4A2 | collagen, type IV, alpha 2 |
| COL7A1 | collagen, type VII, alpha 1 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DRD2 | dopamine receptor D2 |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLJ11292 | |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GP6 | glycoprotein VI (platelet) |
| GPX2 | glutathione peroxidase 2 |
| HFE | hemochromatosis |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AK | histone cluster 1, H2ak |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXA10 | homeobox A10 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ID2B | inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| KIAA1109 | KIAA1109 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NEFM | neurofilament, medium polypeptide |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH12 | protocadherin 12 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PKN2 | protein kinase N2 |
| PLD2 | phospholipase D2 |
| PPID | peptidylprolyl isomerase D |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCARB2 | scavenger receptor class B, member 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS1 | thrombospondin 1 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| VSNL1 | visinin-like 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF639 | zinc finger protein 639 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AMT | aminomethyltransferase |
| APOL6 | apolipoprotein L, 6 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CCDC86 | coiled-coil domain containing 86 |
| CD1C | CD1c molecule |
| CD300C | CD300c molecule |
| CD82 | CD82 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOK3 | docking protein 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR1 | early growth response 1 |
| ELP5 | elongator acetyltransferase complex subunit 5 |
| ENDOG | endonuclease G |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM184A | family with sequence similarity 184, member A |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FHIT | fragile histidine triad |
| FHL3 | four and a half LIM domains 3 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOSL1 | FOS-like antigen 1 |
| FPGS | folylpolyglutamate synthase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| IRX5 | iroquois homeobox 5 |
| KIF21B | kinesin family member 21B |
| LHFP | lipoma HMGIC fusion partner |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MEGF8 | multiple EGF-like-domains 8 |
| METTL8 | methyltransferase like 8 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MOCOS | molybdenum cofactor sulfurase |
| MVD | mevalonate (diphospho) decarboxylase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PRDM13 | PR domain containing 13 |
| PSKH1 | protein serine kinase H1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RFXAP | regulatory factor X-associated protein |
| RGS13 | regulator of G-protein signaling 13 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SALL2 | spalt-like transcription factor 2 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD1A | SET domain containing 1A |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SNAI1 | snail family zinc finger 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STBD1 | starch binding domain 1 |
| STRA13 | stimulated by retinoic acid 13 |
| TERT | telomerase reverse transcriptase |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM134 | transmembrane protein 134 |
| TMEM177 | transmembrane protein 177 |
| TMEM80 | transmembrane protein 80 |
| TNF | tumor necrosis factor |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRIB3 | tribbles pseudokinase 3 |
| UNC119 | unc-119 homolog (C. elegans) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP36 | ubiquitin specific peptidase 36 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF593 | zinc finger protein 593 |
| ZNF667 | zinc finger protein 667 |
| ZNF74 | zinc finger protein 74 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
