| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-6926 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AMBP | alpha-1-microglobulin/bikunin precursor |
| ANKRD6 | ankyrin repeat domain 6 |
| ARTN | artemin |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BMP4 | bone morphogenetic protein 4 |
| BTG2 | BTG family, member 2 |
| CD58 | CD58 molecule |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CSTA | cystatin A (stefin A) |
| CUL4B | cullin 4B |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FAM13C | family with sequence similarity 13, member C |
| FGFR2 | fibroblast growth factor receptor 2 |
| FOSL2 | FOS-like antigen 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GH1 | growth hormone 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HABP2 | hyaluronan binding protein 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMOX1 | heme oxygenase 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KLHL20 | kelch-like family member 20 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP1A | microtubule-associated protein 1A |
| MIR622 | microRNA 622 |
| MXD4 | MAX dimerization protein 4 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NLK | nemo-like kinase |
| NPR3 | natriuretic peptide receptor 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PLA2G3 | phospholipase A2, group III |
| PRSS16 | protease, serine, 16 (thymus) |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RAB11B | RAB11B, member RAS oncogene family |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS2 | regulator of G-protein signaling 2 |
| RHO | rhodopsin |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNF43 | ring finger protein 43 |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1A | sodium channel, voltage gated, type I alpha subunit |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SPRR1A | small proline-rich protein 1A |
| TES | testin LIM domain protein |
| TMEM41B | transmembrane protein 41B |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSPYL2 | TSPY-like 2 |
| ULBP2 | UL16 binding protein 2 |
| USP2 | ubiquitin specific peptidase 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR62 | WD repeat domain 62 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACKR3 | atypical chemokine receptor 3 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) |
| ANKRD36B | ankyrin repeat domain 36B |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL7B | B-cell CLL/lymphoma 7B |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C5 | complement component 5 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CCS | copper chaperone for superoxide dismutase |
| CDKN2AIP | CDKN2A interacting protein |
| CISH | cytokine inducible SH2-containing protein |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COCH | cochlin |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCK | deoxycytidine kinase |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| E2F8 | E2F transcription factor 8 |
| EGR3 | early growth response 3 |
| ERCC8 | excision repair cross-complementation group 8 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FHOD1 | formin homology 2 domain containing 1 |
| FXN | frataxin |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLTP | glycolipid transfer protein |
| GPR19 | G protein-coupled receptor 19 |
| H2AFJ | H2A histone family, member J |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H1D | histone cluster 1, H1d |
| HOXC13 | homeobox C13 |
| ICK | intestinal cell (MAK-like) kinase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IRX5 | iroquois homeobox 5 |
| KLF10 | Kruppel-like factor 10 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LMNB1 | lamin B1 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| METTL8 | methyltransferase like 8 |
| MICALL2 | MICAL-like 2 |
| MOSPD3 | motile sperm domain containing 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPY1R | neuropeptide Y receptor Y1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| OPN3 | opsin 3 |
| OXR1 | oxidation resistance 1 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PLK2 | polo-like kinase 2 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD6 | SET domain containing 6 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SMAD7 | SMAD family member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPAG1 | sperm associated antigen 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPIDR | scaffolding protein involved in DNA repair |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SYTL2 | synaptotagmin-like 2 |
| TESK2 | testis-specific kinase 2 |
| TFB2M | transcription factor B2, mitochondrial |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THAP7 | THAP domain containing 7 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRIM45 | tripartite motif containing 45 |
| TRIM8 | tripartite motif containing 8 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF552 | zinc finger protein 552 |
