| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-6943 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADCY7 | adenylate cyclase 7 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APOM | apolipoprotein M |
| BAG2 | BCL2-associated athanogene 2 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CDC6 | cell division cycle 6 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPOX | coproporphyrinogen oxidase |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ETV5 | ets variant 5 |
| FAM46C | family with sequence similarity 46, member C |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GM2A | GM2 ganglioside activator |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HFE | hemochromatosis |
| HLA-C | major histocompatibility complex, class I, C |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| PRSS16 | protease, serine, 16 (thymus) |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPS3A | ribosomal protein S3A |
| S100A11 | S100 calcium binding protein A11 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERP1 | stress-associated endoplasmic reticulum protein 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETX | senataxin |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SIK1 | salt-inducible kinase 1 |
| SIKE1 | suppressor of IKBKE 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SYNM | synemin, intermediate filament protein |
| TES | testin LIM domain protein |
| TLE4 | transducin-like enhancer of split 4 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TRIM2 | tripartite motif containing 2 |
| TSPYL2 | TSPY-like 2 |
| ULBP2 | UL16 binding protein 2 |
| UNKL | unkempt family zinc finger-like |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| YLPM1 | YLP motif containing 1 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZSCAN12 | zinc finger and SCAN domain containing 12 |
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACKR3 | atypical chemokine receptor 3 |
| ADCY6 | adenylate cyclase 6 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP5J2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACTIN | cactin, spliceosome C complex subunit |
| CDKN2AIP | CDKN2A interacting protein |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DEAF1 | DEAF1 transcription factor |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EDC4 | enhancer of mRNA decapping 4 |
| EGR3 | early growth response 3 |
| FAM155B | family with sequence similarity 155, member B |
| FAM173A | family with sequence similarity 173, member A |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXC1 | forkhead box C1 |
| GPR19 | G protein-coupled receptor 19 |
| HOXC11 | homeobox C11 |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFT22 | intraflagellar transport 22 |
| IL17RB | interleukin 17 receptor B |
| IL4R | interleukin 4 receptor |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRX5 | iroquois homeobox 5 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MPI | mannose phosphate isomerase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NINL | ninein-like |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NVL | nuclear VCP-like |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| POLH | polymerase (DNA directed), eta |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRKCD | protein kinase C, delta |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTK6 | protein tyrosine kinase 6 |
| RAB9A | RAB9A, member RAS oncogene family |
| RGS16 | regulator of G-protein signaling 16 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNMTL1 | RNA methyltransferase like 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD6 | SET domain containing 6 |
| SIRT6 | sirtuin 6 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SPATA2L | spermatogenesis associated 2-like |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase |
| SYTL2 | synaptotagmin-like 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPIN | TIMELESS interacting protein |
| TNS2 | tensin 2 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRIM45 | tripartite motif containing 45 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT61B | tRNA methyltransferase 61B |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN1 | tetraspanin 1 |
| TXLNG | taxilin gamma |
| USP36 | ubiquitin specific peptidase 36 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF239 | zinc finger protein 239 |
| ZNF276 | zinc finger protein 276 |
| ZNF33B | zinc finger protein 33B |
| ZNF675 | zinc finger protein 675 |
| ZNF816 | zinc finger protein 816 |
| ZXDC | ZXD family zinc finger C |
