| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the tanespimycin-6966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADCY7 | adenylate cyclase 7 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| BAG2 | BCL2-associated athanogene 2 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BIN1 | bridging integrator 1 |
| BMP4 | bone morphogenetic protein 4 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACFD1 | calcium channel flower domain containing 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC88A | coiled-coil domain containing 88A |
| CCNG2 | cyclin G2 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CRY2 | cryptochrome circadian clock 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP13 | dual specificity phosphatase 13 |
| DVL3 | dishevelled segment polarity protein 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ESR1 | estrogen receptor 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FZD7 | frizzled class receptor 7 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GM2A | GM2 ganglioside activator |
| GPR35 | G protein-coupled receptor 35 |
| GPR87 | G protein-coupled receptor 87 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
| HMOX1 | heme oxygenase 1 |
| HPCAL4 | hippocalcin like 4 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IRS2 | insulin receptor substrate 2 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAG1 | jagged 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LONP2 | lon peptidase 2, peroxisomal |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP4 | microtubule-associated protein 4 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPT | microtubule-associated protein tau |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED12 | mediator complex subunit 12 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| OSBPL1A | oxysterol binding protein-like 1A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHA6 | protocadherin alpha 6 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RASAL2 | RAS protein activator like 2 |
| RFPL2 | ret finger protein-like 2 |
| RGS14 | regulator of G-protein signaling 14 |
| RGS2 | regulator of G-protein signaling 2 |
| RIN2 | Ras and Rab interactor 2 |
| RNF216 | ring finger protein 216 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETD1A | SET domain containing 1A |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SIRT3 | sirtuin 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TBCD | tubulin folding cofactor D |
| TDRKH | tudor and KH domain containing |
| TES | testin LIM domain protein |
| TK2 | thymidine kinase 2, mitochondrial |
| TRPV4 | transient receptor potential cation channel, subfamily V, member 4 |
| ULBP2 | UL16 binding protein 2 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF227 | zinc finger protein 227 |
| ZNF337 | zinc finger protein 337 |
| ZNF419 | zinc finger protein 419 |
| ZNF614 | zinc finger protein 614 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACKR3 | atypical chemokine receptor 3 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAK1 | BCL2-antagonist/killer 1 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC15 | coiled-coil domain containing 15 |
| CCNE2 | cyclin E2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPJ | centromere protein J |
| CISH | cytokine inducible SH2-containing protein |
| CSAD | cysteine sulfinic acid decarboxylase |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTPS1 | CTP synthase 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DOCK1 | dedicator of cytokinesis 1 |
| DTWD1 | DTW domain containing 1 |
| E2F8 | E2F transcription factor 8 |
| EDC3 | enhancer of mRNA decapping 3 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGR3 | early growth response 3 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EML4 | echinoderm microtubule associated protein like 4 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| EXD2 | exonuclease 3'-5' domain containing 2 |
| FA2H | fatty acid 2-hydroxylase |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FOXD1 | forkhead box D1 |
| FPGS | folylpolyglutamate synthase |
| GAB2 | GRB2-associated binding protein 2 |
| GHR | growth hormone receptor |
| GMIP | GEM interacting protein |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR19 | G protein-coupled receptor 19 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIRA | histone cell cycle regulator |
| HOXC11 | homeobox C11 |
| ICK | intestinal cell (MAK-like) kinase |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IRX4 | iroquois homeobox 4 |
| KLF10 | Kruppel-like factor 10 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCM10 | minichromosome maintenance complex component 10 |
| METTL8 | methyltransferase like 8 |
| MEX3C | mex-3 RNA binding family member C |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MSH2 | mutS homolog 2 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NMD3 | NMD3 ribosome export adaptor |
| NRIP1 | nuclear receptor interacting protein 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARD6B | par-6 family cell polarity regulator beta |
| PLK2 | polo-like kinase 2 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PRKCD | protein kinase C, delta |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC35A5 | solute carrier family 35, member A5 |
| SMAD7 | SMAD family member 7 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYTL2 | synaptotagmin-like 2 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| THOP1 | thimet oligopeptidase 1 |
| TIPIN | TIMELESS interacting protein |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM115 | transmembrane protein 115 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM8 | tripartite motif containing 8 |
| UBA3 | ubiquitin-like modifier activating enzyme 3 |
| URM1 | ubiquitin related modifier 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YEATS2 | YEATS domain containing 2 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZNF331 | zinc finger protein 331 |
