| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-6978 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BMP4 | bone morphogenetic protein 4 |
| BST2 | bone marrow stromal cell antigen 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COPA | coatomer protein complex, subunit alpha |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EFNA3 | ephrin-A3 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ESR1 | estrogen receptor 1 |
| FAM110B | family with sequence similarity 110, member B |
| FAM204A | family with sequence similarity 204, member A |
| FAM212B | family with sequence similarity 212, member B |
| FBXO21 | F-box protein 21 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FZD7 | frizzled class receptor 7 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GSK3A | glycogen synthase kinase 3 alpha |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HOXB5 | homeobox B5 |
| HOXC10 | homeobox C10 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IRS2 | insulin receptor substrate 2 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KIAA0319L | KIAA0319-like |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LDLR | low density lipoprotein receptor |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPIN1 | lipin 1 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAPT | microtubule-associated protein tau |
| MED16 | mediator complex subunit 16 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NEBL | nebulette |
| NF2 | neurofibromin 2 (merlin) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OSBPL1A | oxysterol binding protein-like 1A |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PER1 | period circadian clock 1 |
| PLXNA3 | plexin A3 |
| PMCH | pro-melanin-concentrating hormone |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| QKI | QKI, KH domain containing, RNA binding |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TES | testin LIM domain protein |
| TMEM53 | transmembrane protein 53 |
| TRIM2 | tripartite motif containing 2 |
| TSPYL2 | TSPY-like 2 |
| ULBP2 | UL16 binding protein 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR1 | WD repeat domain 1 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF329 | zinc finger protein 329 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ANKRD36B | ankyrin repeat domain 36B |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP13A2 | ATPase type 13A2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCNE2 | cyclin E2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CXORF56 | chromosome X open reading frame 56 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| ECD | ecdysoneless homolog (Drosophila) |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EGR3 | early growth response 3 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPS8L2 | EPS8-like 2 |
| EVL | Enah/Vasp-like |
| FAM50B | family with sequence similarity 50, member B |
| FAM57A | family with sequence similarity 57, member A |
| FHOD1 | formin homology 2 domain containing 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXD1 | forkhead box D1 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFT88 | intraflagellar transport 88 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KLC2 | kinesin light chain 2 |
| KLF10 | Kruppel-like factor 10 |
| LAMA3 | laminin, alpha 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP6D1 | MAP6 domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED22 | mediator complex subunit 22 |
| MEX3C | mex-3 RNA binding family member C |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MNT | MAX network transcriptional repressor |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCAM2 | neural cell adhesion molecule 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PODXL | podocalyxin-like |
| PUS1 | pseudouridylate synthase 1 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM14 | RNA binding motif protein 14 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD6 | SET domain containing 6 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SYTL2 | synaptotagmin-like 2 |
| TCTA | T-cell leukemia translocation altered |
| TFRC | transferrin receptor |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TRAF5 | TNF receptor-associated factor 5 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UBA3 | ubiquitin-like modifier activating enzyme 3 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF124 | zinc finger protein 124 |
| ZNF787 | zinc finger protein 787 |
| ZXDC | ZXD family zinc finger C |
