tanespimycin-6985 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the tanespimycin-6985 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADCY7 adenylate cyclase 7
ADM adrenomedullin
ANXA2P3 annexin A2 pseudogene 3
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARL4D ADP-ribosylation factor-like 4D
BAG2 BCL2-associated athanogene 2
BGN biglycan
BST1 bone marrow stromal cell antigen 1
BTG2 BTG family, member 2
BTN2A2 butyrophilin, subfamily 2, member A2
C11ORF73 chromosome 11 open reading frame 73
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLEC11A C-type lectin domain family 11, member A
COL6A1 collagen, type VI, alpha 1
CSRP2 cysteine and glycine-rich protein 2
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DTNA dystrobrevin, alpha
EMID1 EMI domain containing 1
EPOR erythropoietin receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
FGFR2 fibroblast growth factor receptor 2
FXR1 fragile X mental retardation, autosomal homolog 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOSR2 golgi SNAP receptor complex member 2
GPR87 G protein-coupled receptor 87
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFNA14 interferon, alpha 14
IGFBP3 insulin-like growth factor binding protein 3
INPP5J inositol polyphosphate-5-phosphatase J
IRS2 insulin receptor substrate 2
JAK2 Janus kinase 2
LTBP2 latent transforming growth factor beta binding protein 2
MALT1 MALT1 paracaspase
MED6 mediator complex subunit 6
METTL7A methyltransferase like 7A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MXD4 MAX dimerization protein 4
N4BP2L2 NEDD4 binding protein 2-like 2
NAP1L2 nucleosome assembly protein 1-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NEU3 sialidase 3 (membrane sialidase)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NNAT neuronatin
NPR3 natriuretic peptide receptor 3
ORC5 origin recognition complex, subunit 5
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDE4DIP phosphodiesterase 4D interacting protein
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G3 phospholipase A2, group III
PODNL1 podocan-like 1
PODXL2 podocalyxin-like 2
PRB1 proline-rich protein BstNI subfamily 1
PRPF18 pre-mRNA processing factor 18
RCAN1 regulator of calcineurin 1
RCAN3 RCAN family member 3
RFPL2 ret finger protein-like 2
RFPL3 ret finger protein-like 3
RGS2 regulator of G-protein signaling 2
RRBP1 ribosome binding protein 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SIKE1 suppressor of IKBKE 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TP53I11 tumor protein p53 inducible protein 11
TRA T cell receptor alpha locus
TSPYL2 TSPY-like 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF136 zinc finger protein 136
ZNF165 zinc finger protein 165
ZNF227 zinc finger protein 227
ZNF37BP zinc finger protein 37B, pseudogene
ZNF407 zinc finger protein 407
ZNF419 zinc finger protein 419
ZNF571 zinc finger protein 571

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRA3 adhesion G protein-coupled receptor A3
ANKRD36B ankyrin repeat domain 36B
ASTE1 asteroid homolog 1 (Drosophila)
BCOR BCL6 corepressor
BIK BCL2-interacting killer (apoptosis-inducing)
BLM Bloom syndrome, RecQ helicase-like
BOLA1 bolA family member 1
C10ORF88 chromosome 10 open reading frame 88
C11ORF95 chromosome 11 open reading frame 95
C12ORF4 chromosome 12 open reading frame 4
CD3EAP CD3e molecule, epsilon associated protein
CDK3 cyclin-dependent kinase 3
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COA7 cytochrome c oxidase assembly factor 7 (putative)
CPTP ceramide-1-phosphate transfer protein
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTSK cathepsin K
DNAAF2 dynein, axonemal, assembly factor 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F8 E2F transcription factor 8
EGR3 early growth response 3
EML4 echinoderm microtubule associated protein like 4
ESRP2 epithelial splicing regulatory protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FOXD1 forkhead box D1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPR19 G protein-coupled receptor 19
HIRA histone cell cycle regulator
HTRA2 HtrA serine peptidase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
JUNB jun B proto-oncogene
LAMA3 laminin, alpha 3
LIN37 lin-37 DREAM MuvB core complex component
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MCM10 minichromosome maintenance complex component 10
MFSD12 major facilitator superfamily domain containing 12
MOCS3 molybdenum cofactor synthesis 3
MXD3 MAX dimerization protein 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCAM2 neural cell adhesion molecule 2
NPY5R neuropeptide Y receptor Y5
NUPL2 nucleoporin like 2
NXT1 nuclear transport factor 2-like export factor 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PALB2 partner and localizer of BRCA2
PARD6A par-6 family cell polarity regulator alpha
PCF11 PCF11 cleavage and polyadenylation factor subunit
PGP phosphoglycolate phosphatase
PLA2G15 phospholipase A2, group XV
PLD3 phospholipase D family, member 3
PLK2 polo-like kinase 2
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PUS1 pseudouridylate synthase 1
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBM14 RNA binding motif protein 14
RECQL4 RecQ protein-like 4
REPS2 RALBP1 associated Eps domain containing 2
RGS16 regulator of G-protein signaling 16
RGS19 regulator of G-protein signaling 19
RIBC2 RIB43A domain with coiled-coils 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SDCCAG3 serologically defined colon cancer antigen 3
SETMAR SET domain and mariner transposase fusion gene
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SMAD7 SMAD family member 7
SPATA2L spermatogenesis associated 2-like
STBD1 starch binding domain 1
STK25 serine/threonine kinase 25
SYTL2 synaptotagmin-like 2
TFRC transferrin receptor
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TIPIN TIMELESS interacting protein
TOLLIP toll interacting protein
TRAF5 TNF receptor-associated factor 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBL4A ubiquitin-like 4A
WDR76 WD repeat domain 76
ZBTB25 zinc finger and BTB domain containing 25
ZNF232 zinc finger protein 232
ZNF239 zinc finger protein 239
ZNF692 zinc finger protein 692
ZNF8 zinc finger protein 8
ZXDC ZXD family zinc finger C