| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the tanespimycin-986 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATXN3 | ataxin 3 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BMP2K | BMP2 inducible kinase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA11 | carbonic anhydrase XI |
| CA4 | carbonic anhydrase IV |
| CABIN1 | calcineurin binding protein 1 |
| CCNG2 | cyclin G2 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDH8 | cadherin 8, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL1A2 | collagen, type I, alpha 2 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DBF4B | DBF4 zinc finger B |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DSPP | dentin sialophosphoprotein |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EMID1 | EMI domain containing 1 |
| ERP44 | endoplasmic reticulum protein 44 |
| FAM46C | family with sequence similarity 46, member C |
| FHL1 | four and a half LIM domains 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GLRX | glutaredoxin (thioltransferase) |
| GNAS | GNAS complex locus |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP1B | microtubule-associated protein 1B |
| METTL5 | methyltransferase like 5 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAG18 | NAG18 mRNA |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NF2 | neurofibromin 2 (merlin) |
| NRF1 | nuclear respiratory factor 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAX8 | paired box 8 |
| PCDHA5 | protocadherin alpha 5 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLK4 | polo-like kinase 4 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAPSN | receptor-associated protein of the synapse |
| RBM5 | RNA binding motif protein 5 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RGS12 | regulator of G-protein signaling 12 |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS3A | ribosomal protein S3A |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLAMF7 | SLAM family member 7 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPRR1A | small proline-rich protein 1A |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK17B | serine/threonine kinase 17b |
| TES | testin LIM domain protein |
| TIGD6 | tigger transposable element derived 6 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TRIM2 | tripartite motif containing 2 |
| TSGA10 | testis specific, 10 |
| TSPYL2 | TSPY-like 2 |
| TSSK2 | testis-specific serine kinase 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| ZNF165 | zinc finger protein 165 |
| ZNF222 | zinc finger protein 222 |
| ZNF227 | zinc finger protein 227 |
| ZNF350 | zinc finger protein 350 |
| ZNF419 | zinc finger protein 419 |
| ZNF571 | zinc finger protein 571 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACKR3 | atypical chemokine receptor 3 |
| ADCK3 | aarF domain containing kinase 3 |
| ADCY6 | adenylate cyclase 6 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ANKRD28 | ankyrin repeat domain 28 |
| ARRB2 | arrestin, beta 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTBD2 | BTB (POZ) domain containing 2 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC15 | coiled-coil domain containing 15 |
| CCNE1 | cyclin E1 |
| CDCA4 | cell division cycle associated 4 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DNM1 | dynamin 1 |
| DNMBP | dynamin binding protein |
| DSCAM | Down syndrome cell adhesion molecule |
| E2F1 | E2F transcription factor 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FAM63A | family with sequence similarity 63, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHOD1 | formin homology 2 domain containing 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXC1 | forkhead box C1 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR19 | G protein-coupled receptor 19 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| H2AFY2 | H2A histone family, member Y2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| INPP5F | inositol polyphosphate-5-phosphatase F |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| JADE1 | jade family PHD finger 1 |
| JUNB | jun B proto-oncogene |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| METTL8 | methyltransferase like 8 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MOAP1 | modulator of apoptosis 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUPL2 | nucleoporin like 2 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PLD3 | phospholipase D family, member 3 |
| PMM1 | phosphomannomutase 1 |
| PRR7 | proline rich 7 (synaptic) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RBM14 | RNA binding motif protein 14 |
| RBM38 | RNA binding motif protein 38 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STBD1 | starch binding domain 1 |
| SYTL2 | synaptotagmin-like 2 |
| TEAD4 | TEA domain family member 4 |
| TELO2 | telomere maintenance 2 |
| TIPIN | TIMELESS interacting protein |
| TMEM62 | transmembrane protein 62 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZXDC | ZXD family zinc finger C |
