tanshinone-iia Gene Set
Genes
49 genes differentially expressed following the tanshinone-iia small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CLIC1
|
chloride intracellular channel 1
|
3.68253
|
|
LOX
|
lysyl oxidase
|
3.59269
|
|
DCAF10
|
DDB1 and CUL4 associated factor 10
|
3.47779
|
|
RSL1D1
|
ribosomal L1 domain containing 1
|
3.41876
|
|
UBE2I
|
ubiquitin-conjugating enzyme E2I
|
3.3984
|
|
UNKL
|
unkempt family zinc finger-like
|
3.35082
|
|
ABCC3
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
|
3.3471
|
|
BCAR3
|
breast cancer anti-estrogen resistance 3
|
3.32856
|
|
PSORS1C2
|
psoriasis susceptibility 1 candidate 2
|
3.30258
|
|
CCR6
|
chemokine (C-C motif) receptor 6
|
3.29412
|
|
SIPA1L3
|
signal-induced proliferation-associated 1 like 3
|
3.25847
|
|
INHA
|
inhibin, alpha
|
3.24329
|
|
SS18
|
synovial sarcoma translocation, chromosome 18
|
3.24265
|
|
METTL9
|
methyltransferase like 9
|
3.22239
|
|
BRAF
|
B-Raf proto-oncogene, serine/threonine kinase
|
3.13589
|
|
KLF3
|
Kruppel-like factor 3 (basic)
|
3.13126
|
|
SNHG32
|
small nucleolar RNA host gene 32
|
3.08465
|
|
AXIN1
|
axin 1
|
3.08227
|
|
MTF2
|
metal response element binding transcription factor 2
|
3.07887
|
|
UGGT2
|
UDP-glucose glycoprotein glucosyltransferase 2
|
3.07092
|
|
PSMD8
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
|
3.06796
|
|
GMEB1
|
glucocorticoid modulatory element binding protein 1
|
3.0664
|
|
PRKCH
|
protein kinase C, eta
|
3.06209
|
|
TNFRSF13B
|
tumor necrosis factor receptor superfamily, member 13B
|
3.05068
|
|
OSMR
|
oncostatin M receptor
|
3.04513
|
|
MEX3D
|
mex-3 RNA binding family member D
|
3.03502
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.02588
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
-4.79581
|
|
ECM1
|
extracellular matrix protein 1
|
-3.92108
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
-3.76671
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
-3.48502
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
-3.48317
|
|
SRSF6
|
serine/arginine-rich splicing factor 6
|
-3.48262
|
|
DGLUCY
|
D-glutamate cyclase
|
-3.44458
|
|
POGLUT1
|
protein O-glucosyltransferase 1
|
-3.43016
|
|
HSD17B4
|
hydroxysteroid (17-beta) dehydrogenase 4
|
-3.24601
|
|
NPAS3
|
neuronal PAS domain protein 3
|
-3.24533
|
|
KIF11
|
kinesin family member 11
|
-3.22401
|
|
SPEN
|
spen family transcriptional repressor
|
-3.19025
|
|
LRPPRC
|
leucine-rich pentatricopeptide repeat containing
|
-3.18756
|
|
KHSRP
|
KH-type splicing regulatory protein
|
-3.17336
|
|
INSM1
|
insulinoma-associated 1
|
-3.16355
|
|
POLQ
|
polymerase (DNA directed), theta
|
-3.149
|
|
CEP72
|
centrosomal protein 72kDa
|
-3.14056
|
|
CPNE3
|
copine III
|
-3.10336
|
|
MAD1L1
|
MAD1 mitotic arrest deficient-like 1 (yeast)
|
-3.05854
|
|
CBR4
|
carbonyl reductase 4
|
-3.02942
|
|
TMEM97
|
transmembrane protein 97
|
-3.01015
|
|
SNX4
|
sorting nexin 4
|
-3.00893
|
