targeting Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

386 proteins co-occuring with the biological term targeting in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ADAM22 ADAM metallopeptidase domain 22
ADD1 adducin 1 (alpha)
ADD3 adducin 3 (gamma)
ADORA2A adenosine A2a receptor
ADRB1 adrenoceptor beta 1
AGA aspartylglucosaminidase
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANKRD28 ankyrin repeat domain 28
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
AQP4 aquaporin 4
AQP5 aquaporin 5
AR androgen receptor
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARRB1 arrestin, beta 1
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
AURKA aurora kinase A
AURKB aurora kinase B
AVPR2 arginine vasopressin receptor 2
BAD BCL2-associated agonist of cell death
BARD1 BRCA1 associated RING domain 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BIRC5 baculoviral IAP repeat containing 5
BLVRA biliverdin reductase A
BMF Bcl2 modifying factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRSK2 BR serine/threonine kinase 2
BTK Bruton agammaglobulinemia tyrosine kinase
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX5 chromobox homolog 5
CCDC6 coiled-coil domain containing 6
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CCNB1 cyclin B1
CCND1 cyclin D1
CCNH cyclin H
CD1D CD1d molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC5L cell division cycle 5-like
CDCA2 cell division cycle associated 2
CDCA8 cell division cycle associated 8
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK16 cyclin-dependent kinase 16
CDK2 cyclin-dependent kinase 2
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPA centromere protein A
CENPU centromere protein U
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CIITA class II, major histocompatibility complex, transactivator
CLDN2 claudin 2
CLDN5 claudin 5
CNN3 calponin 3, acidic
CORO7 coronin 7
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF1R colony stimulating factor 1 receptor
CSF3R colony stimulating factor 3 receptor (granulocyte)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CYCS cytochrome c, somatic
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYTH3 cytohesin 3
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCLRE1C DNA cross-link repair 1C
DCTN1 dynactin 1
DCX doublecortin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKA diacylglycerol kinase, alpha 80kDa
DLG1 discs, large homolog 1 (Drosophila)
DNM1L dynamin 1-like
DNM2 dynamin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK1 dedicator of cytokinesis 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYSL2 dihydropyrimidinase-like 2
DUSP12 dual specificity phosphatase 12
DYNLT1 dynein, light chain, Tctex-type 1
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELMO1 engulfment and cell motility 1
EMD emerin
EPB41 erythrocyte membrane protein band 4.1
EPHA8 EPH receptor A8
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FBXL2 F-box and leucine-rich repeat protein 2
FBXW5 F-box and WD repeat domain containing 5
FEN1 flap structure-specific endonuclease 1
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GMNN geminin, DNA replication inhibitor
GPSM2 G-protein signaling modulator 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM5 glutamate receptor, metabotropic 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTA4 glutathione S-transferase alpha 4
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC7 histone deacetylase 7
HIST1H2AI histone cluster 1, H2ai
HIST1H3A histone cluster 1, H3a
HMGN1 high mobility group nucleosome binding domain 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HTT huntingtin
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6ST interleukin 6 signal transducer
INCENP inner centromere protein antigens 135/155kDa
INPPL1 inositol polyphosphate phosphatase-like 1
IRF2BP2 interferon regulatory factor 2 binding protein 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITPKA inositol-trisphosphate 3-kinase A
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JDP2 Jun dimerization protein 2
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNK9 potassium channel, two pore domain subfamily K, member 9
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KDR kinase insert domain receptor
KIF13B kinesin family member 13B
KIF2C kinesin family member 2C
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
LCK LCK proto-oncogene, Src family tyrosine kinase
LEMD3 LEM domain containing 3
LIG1 ligase I, DNA, ATP-dependent
LIPE lipase, hormone-sensitive
LMTK1 lemur tail kinase 1
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPXN leupaxin
LRRK2 leucine-rich repeat kinase 2
LTB4R leukotriene B4 receptor
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MBP myelin basic protein
MCL1 myeloid cell leukemia 1
MCTS1 malignant T cell amplified sequence 1
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MITF microphthalmia-associated transcription factor
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTMR2 myotubularin related protein 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYL12B myosin, light chain 12B, regulatory
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
MYOM2 myomesin 2
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEFL neurofilament, light polypeptide
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHP1 nephronophthisis 1 (juvenile)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRIP1 nuclear receptor interacting protein 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUSAP1 nucleolar and spindle associated protein 1
OCLN occludin
OPRD1 opioid receptor, delta 1
OPTN optineurin
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PFN1 profilin 1
PGR progesterone receptor
PIAS2 protein inhibitor of activated STAT, 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITPNB phosphatidylinositol transfer protein, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLK1 polo-like kinase 1
PLN phospholamban
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSIP1 PC4 and SFRS1 interacting protein 1
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTRF polymerase I and transcript release factor
PTTG1 pituitary tumor-transforming 1
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXN paxillin
PYGB phosphorylase, glycogen; brain
RAB24 RAB24, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP3 RAN binding protein 3
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RBM4 RNA binding motif protein 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS16 regulator of G-protein signaling 16
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHOU ras homolog family member U
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SAMHD1 SAM domain and HD domain 1
SCN2A sodium channel, voltage gated, type II alpha subunit
SGK1 serum/glucocorticoid regulated kinase 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SKAP2 src kinase associated phosphoprotein 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMC1A structural maintenance of chromosomes 1A
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTA1 syntrophin, alpha 1
SNX18 sorting nexin 18
SP1 Sp1 transcription factor
SPAG5 sperm associated antigen 5
SPHK1 sphingosine kinase 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF5 serine/arginine-rich splicing factor 5
SSTR2 somatostatin receptor 2
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STK38 serine/threonine kinase 38
STMN1 stathmin 1
SYK spleen tyrosine kinase
TACC3 transforming, acidic coiled-coil containing protein 3
TBC1D4 TBC1 domain family, member 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLK1 tousled-like kinase 1
TNIK TRAF2 and NCK interacting kinase
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TRHR thyrotropin-releasing hormone receptor
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSC2 tuberous sclerosis 2
TTC5 tetratricopeptide repeat domain 5
TTK TTK protein kinase
USO1 USO1 vesicle transport factor
VASP vasodilator-stimulated phosphoprotein
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
YBX1 Y box binding protein 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZC3HC1 zinc finger, C3HC-type containing 1
ZFP36L1 ZFP36 ring finger protein-like 1