tcf3_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE19923
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Genes

129 genes differentially expressed following the tcf3_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
KIAA1109 KIAA1109 0.208234
MIR186 microRNA 186 0.197382
ANO10 anoctamin 10 0.193968
EPS15 epidermal growth factor receptor pathway substrate 15 0.184008
EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 0.178022
PLA2G2C phospholipase A2, group IIC 0.167666
RNF111 ring finger protein 111 0.165548
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.157667
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.155466
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 0.147622
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 0.146742
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 0.145998
MARCKS myristoylated alanine-rich protein kinase C substrate 0.142326
CNOT1 CCR4-NOT transcription complex, subunit 1 0.13703
MED1 mediator complex subunit 1 0.123422
MPHOSPH6 M-phase phosphoprotein 6 0.109173
KDM4C lysine (K)-specific demethylase 4C 0.105262
CCDC180 coiled-coil domain containing 180 0.104988
RPS2 ribosomal protein S2 0.088163
KLHL7 kelch-like family member 7 0.087663
PRRC2C proline-rich coiled-coil 2C 0.076093
MTX3 metaxin 3 0.075765
RAD18 RAD18 E3 ubiquitin protein ligase 0.062585
NT5M 5',3'-nucleotidase, mitochondrial 0.059701
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.052668
UBXN6 UBX domain protein 6 0.052342
MPC2 mitochondrial pyruvate carrier 2 0.050987
ZBTB34 zinc finger and BTB domain containing 34 0.045196
CDV3 CDV3 homolog (mouse) 0.041338
SPG11 spastic paraplegia 11 (autosomal recessive) 0.027693
ADD3 adducin 3 (gamma) 0.014203
YIPF4 Yip1 domain family, member 4 0.013018
SFT2D3 SFT2 domain containing 3 0.010053

decreased expression

Symbol Name Standardized Value
MIB2 mindbomb E3 ubiquitin protein ligase 2 -1.30452
BLVRB biliverdin reductase B -1.28253
OLFML3 olfactomedin-like 3 -1.25843
NTSR2 neurotensin receptor 2 -1.24799
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -1.21757
RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1 -1.18172
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 -1.17832
TTLL11 tubulin tyrosine ligase-like family member 11 -1.1666
MECOM MDS1 and EVI1 complex locus -1.15873
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -1.15273
SPHKAP SPHK1 interactor, AKAP domain containing -1.13974
EFNB3 ephrin-B3 -1.09422
TM7SF2 transmembrane 7 superfamily member 2 -1.08619
PDCD1 programmed cell death 1 -1.06226
ANK2 ankyrin 2, neuronal -1.00236
SYMPK symplekin -0.999465
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 -0.98992
LCE3B late cornified envelope 3B -0.978913
IGFBP1 insulin-like growth factor binding protein 1 -0.964004
MIR299 microRNA 299 -0.955559
PLXND1 plexin D1 -0.943424
STXBP5L syntaxin binding protein 5-like -0.926359
SYT15 synaptotagmin XV -0.919616
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 -0.904632
FGF7 fibroblast growth factor 7 -0.889148
SMIM5 small integral membrane protein 5 -0.886639
ZFP36 ZFP36 ring finger protein -0.881684
MRPS11 mitochondrial ribosomal protein S11 -0.878368
MMP3 matrix metallopeptidase 3 -0.842843
DUSP18 dual specificity phosphatase 18 -0.815114
RNF187 ring finger protein 187 -0.741516
XK X-linked Kx blood group -0.734942
HMCN1 hemicentin 1 -0.731712
ERCC2 excision repair cross-complementation group 2 -0.728302
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.727689
MMP15 matrix metallopeptidase 15 (membrane-inserted) -0.722369
RPL18 ribosomal protein L18 -0.704719
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -0.698318
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -0.692018
ENAH enabled homolog (Drosophila) -0.681829
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -0.680774
PILRA paired immunoglobin-like type 2 receptor alpha -0.670421
TMEM25 transmembrane protein 25 -0.665958
GPR141 G protein-coupled receptor 141 -0.6628
ADAM2 ADAM metallopeptidase domain 2 -0.658293
EXOC3L4 exocyst complex component 3-like 4 -0.642691
FGD5 FYVE, RhoGEF and PH domain containing 5 -0.640879
ZFYVE27 zinc finger, FYVE domain containing 27 -0.639368
DPY19L2 dpy-19-like 2 (C. elegans) -0.630988
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.622473
TRAFD1 TRAF-type zinc finger domain containing 1 -0.620157
MRPL17 mitochondrial ribosomal protein L17 -0.618126
SIK1 salt-inducible kinase 1 -0.617522
MYL10 myosin, light chain 10, regulatory -0.615713
ALX1 ALX homeobox 1 -0.612519
SPEF2 sperm flagellar 2 -0.585557
PPT2 palmitoyl-protein thioesterase 2 -0.584288
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -0.57216
VWA5B2 von Willebrand factor A domain containing 5B2 -0.556665
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.547236
RSG1 REM2 and RAB-like small GTPase 1 -0.547132
TBXA2R thromboxane A2 receptor -0.535015
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 -0.525461
RBM6 RNA binding motif protein 6 -0.502222
OR4C45 olfactory receptor, family 4, subfamily C, member 45 -0.497069
LHX4 LIM homeobox 4 -0.495228
AFM afamin -0.491349
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -0.476071
SLC26A8 solute carrier family 26 (anion exchanger), member 8 -0.475284
ODF4 outer dense fiber of sperm tails 4 -0.472159
RNF223 ring finger protein 223 -0.468227
ADAM5 ADAM metallopeptidase domain 5 (pseudogene) -0.467081
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -0.46317
PIAS4 protein inhibitor of activated STAT, 4 -0.462243
KLHL40 kelch-like family member 40 -0.462051
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.457938
LMLN leishmanolysin-like (metallopeptidase M8 family) -0.456522
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.455496
CASC1 cancer susceptibility candidate 1 -0.455376
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.45427
POU4F3 POU class 4 homeobox 3 -0.454061
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 -0.451422
OR4N5 olfactory receptor, family 4, subfamily N, member 5 -0.444665
TRDN triadin -0.440009
ZNF250 zinc finger protein 250 -0.432378
CHUK conserved helix-loop-helix ubiquitous kinase -0.061343
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.052322
ZNF266 zinc finger protein 266 -0.052086
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.048738
OR6C68 olfactory receptor, family 6, subfamily C, member 68 -0.047062
ANKRD11 ankyrin repeat domain 11 -0.040566
ASB7 ankyrin repeat and SOCS box containing 7 -0.036405
HEG1 heart development protein with EGF-like domains 1 -0.023385
ODC1 ornithine decarboxylase 1 -0.021317
RPL12 ribosomal protein L12 -0.013409
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.011546
Funding