tcf7l2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description transcription factor 7-like 2 (T-cell specific, HMG-box)|This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 6934)
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Genes

38 genes co-occuring with the biological term tcf7l2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AXIN1 axin 1
AXIN2 axin 2
C4ORF32 chromosome 4 open reading frame 32
CCAT2 colon cancer associated transcript 2 (non-protein coding)
CCND1 cyclin D1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CTSB cathepsin B
CXCR4 chemokine (C-X-C motif) receptor 4
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FOXA2 forkhead box A2
FTO fat mass and obesity associated
GATA3 GATA binding protein 3
GCG glucagon
GHSR growth hormone secretagogue receptor
GIPR gastric inhibitory polypeptide receptor
GLP1R glucagon-like peptide 1 receptor
HHEX hematopoietically expressed homeobox
HNF4A hepatocyte nuclear factor 4, alpha
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEUROG3 neurogenin 3
POU5F1B POU class 5 homeobox 1B
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RPL21P7 ribosomal protein L21 pseudogene 7
RXRA retinoid X receptor, alpha
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SPINK1 serine peptidase inhibitor, Kazal type 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THADA thyroid adenoma associated
WNT16 wingless-type MMTV integration site family, member 16
WWC1 WW and C2 domain containing 1