tec Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description tec protein tyrosine kinase|The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7006)
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Genes

23 genes co-occuring with the biological term tec in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BMX BMX non-receptor tyrosine kinase
BTK Bruton agammaglobulinemia tyrosine kinase
CD28 CD28 molecule
CXCR4 chemokine (C-X-C motif) receptor 4
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
EWSR1 EWS RNA-binding protein 1
FGF2 fibroblast growth factor 2 (basic)
IFNGR1 interferon gamma receptor 1
IL6 interleukin 6
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPPL1 inositol polyphosphate phosphatase-like 1
ITK IL2-inducible T-cell kinase
NRP2 neuropilin 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
SBSN suprabasin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TEC tec protein tyrosine kinase
TFG TRK-fused gene
TLR4 toll-like receptor 4