| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the telenzepine-5096 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGO4 | argonaute RISC catalytic component 4 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BGN | biglycan |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAPN3 | calpain 3, (p94) |
| CCDC28B | coiled-coil domain containing 28B |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD58 | CD58 molecule |
| CD68 | CD68 molecule |
| CDHR2 | cadherin-related family member 2 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEMP1 | cementum protein 1 |
| CEP295 | centrosomal protein 295kDa |
| CFHR2 | complement factor H-related 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DALRD3 | DALR anticodon binding domain containing 3 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DRICH1 | aspartate-rich 1 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| ENG | endoglin |
| ESR1 | estrogen receptor 1 |
| EXOSC2 | exosome component 2 |
| FOXN3 | forkhead box N3 |
| GAS7 | growth arrest-specific 7 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GK3P | glycerol kinase 3 pseudogene |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPR1 | G protein-coupled receptor 1 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HDAC7 | histone deacetylase 7 |
| HHAT | hedgehog acyltransferase |
| HIC2 | hypermethylated in cancer 2 |
| HOXB5 | homeobox B5 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INE1 | inactivation escape 1 (non-protein coding) |
| KIAA1456 | KIAA1456 |
| KRT8P12 | keratin 8 pseudogene 12 |
| KRTAP1-3 | keratin associated protein 1-3 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MDFI | MyoD family inhibitor |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MYO1B | myosin IB |
| MYO1F | myosin IF |
| NFIB | nuclear factor I/B |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NNMT | nicotinamide N-methyltransferase |
| NPR1 | natriuretic peptide receptor 1 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NRXN2 | neurexin 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDLIM5 | PDZ and LIM domain 5 |
| PDZK1 | PDZ domain containing 1 |
| PODNL1 | podocan-like 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB26 | RAB26, member RAS oncogene family |
| RARG | retinoic acid receptor, gamma |
| RBM12B | RNA binding motif protein 12B |
| SAMD9 | sterile alpha motif domain containing 9 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SH2B1 | SH2B adaptor protein 1 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| THOC5 | THO complex 5 |
| TLR4 | toll-like receptor 4 |
| TNPO3 | transportin 3 |
| TNS1 | tensin 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBE3A | ubiquitin protein ligase E3A |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AK5 | adenylate kinase 5 |
| ANXA10 | annexin A10 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BEX1 | brain expressed, X-linked 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CAPN15 | calpain 15 |
| CDIP1 | cell death-inducing p53 target 1 |
| CDK6 | cyclin-dependent kinase 6 |
| CENPJ | centromere protein J |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DENND4A | DENN/MADD domain containing 4A |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FXN | frataxin |
| GALT | galactose-1-phosphate uridylyltransferase |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSR | glutathione reductase |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOXA1 | homeobox A1 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| IFI44L | interferon-induced protein 44-like |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL22 | interleukin 22 |
| JUNB | jun B proto-oncogene |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA0319L | KIAA0319-like |
| KIAA1549L | KIAA1549-like |
| KRT86 | keratin 86, type II |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEH1 | melanoma antigen family H1 |
| MED15 | mediator complex subunit 15 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3B | mucin 3B, cell surface associated |
| MX1 | MX dynamin-like GTPase 1 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRSN2 | neurensin 2 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PALMD | palmdelphin |
| PGPEP1 | pyroglutamyl-peptidase I |
| PID1 | phosphotyrosine interaction domain containing 1 |
| POLL | polymerase (DNA directed), lambda |
| PTK6 | protein tyrosine kinase 6 |
| QSER1 | glutamine and serine rich 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SETBP1 | SET binding protein 1 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SHPK | sedoheptulokinase |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SPAG16 | sperm associated antigen 16 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SRBD1 | S1 RNA binding domain 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TEAD3 | TEA domain family member 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM242 | transmembrane protein 242 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM25 | tripartite motif containing 25 |
| TUBG2 | tubulin, gamma 2 |
| TXK | TXK tyrosine kinase |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR18 | WD repeat domain 18 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF225 | zinc finger protein 225 |
| ZNF254 | zinc finger protein 254 |
| ZNF34 | zinc finger protein 34 |
| ZNF668 | zinc finger protein 668 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF816 | zinc finger protein 816 |