| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the telenzepine-5521 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AQP1 | aquaporin 1 (Colton blood group) |
| AREG | amphiregulin |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARTN | artemin |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| C9ORF16 | chromosome 9 open reading frame 16 |
| CABIN1 | calcineurin binding protein 1 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC14B | cell division cycle 14B |
| CDK14 | cyclin-dependent kinase 14 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLIC5 | chloride intracellular channel 5 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DIO2 | deiodinase, iodothyronine, type II |
| DUSP10 | dual specificity phosphatase 10 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FRMD1 | FERM domain containing 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIST1H3B | histone cluster 1, H3b |
| HRH4 | histamine receptor H4 |
| IFFO1 | intermediate filament family orphan 1 |
| IFT38 | intraflagellar transport 38 |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IPO5 | importin 5 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KAT8 | K(lysine) acetyltransferase 8 |
| KHK | ketohexokinase (fructokinase) |
| KIAA0930 | KIAA0930 |
| KLF12 | Kruppel-like factor 12 |
| KRT17 | keratin 17, type I |
| KRT37 | keratin 37, type I |
| KRTAP9-9 | keratin associated protein 9-9 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMAN1 | lectin, mannose-binding, 1 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MMP25 | matrix metallopeptidase 25 |
| MOG | myelin oligodendrocyte glycoprotein |
| MYEF2 | myelin expression factor 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRAMEF10 | PRAME family member 10 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRSS3 | protease, serine, 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RRBP1 | ribosome binding protein 1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SFTPC | surfactant protein C |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SPRR1B | small proline-rich protein 1B |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYT11 | synaptotagmin XI |
| TBC1D22A | TBC1 domain family, member 22A |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| UTRN | utrophin |
| VGF | VGF nerve growth factor inducible |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WSCD1 | WSC domain containing 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF862 | zinc finger protein 862 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| AFF4 | AF4/FMR2 family, member 4 |
| ALPK1 | alpha-kinase 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATG9A | autophagy related 9A |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAPRIN2 | caprin family member 2 |
| CBX4 | chromobox homolog 4 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC186 | coiled-coil domain containing 186 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CISH | cytokine inducible SH2-containing protein |
| CLDN4 | claudin 4 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTSK | cathepsin K |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| EFNA3 | ephrin-A3 |
| EPHA2 | EPH receptor A2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM192A | family with sequence similarity 192, member A |
| FBXO22 | F-box protein 22 |
| FILIP1L | filamin A interacting protein 1-like |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GID4 | GID complex subunit 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HCFC2 | host cell factor C2 |
| HIRA | histone cell cycle regulator |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H4D | histone cluster 1, H4d |
| HOXC10 | homeobox C10 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IFT81 | intraflagellar transport 81 |
| IL15RA | interleukin 15 receptor, alpha |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JUNB | jun B proto-oncogene |
| KLF11 | Kruppel-like factor 11 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MANBA | mannosidase, beta A, lysosomal |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED24 | mediator complex subunit 24 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| MOSPD3 | motile sperm domain containing 3 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLIN3 | perilipin 3 |
| PROS1 | protein S (alpha) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SFT2D2 | SFT2 domain containing 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SPHK1 | sphingosine kinase 1 |
| STBD1 | starch binding domain 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM254 | transmembrane protein 254 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSPAN1 | tetraspanin 1 |
| UBQLN4 | ubiquilin 4 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR19 | WD repeat domain 19 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF573 | zinc finger protein 573 |
| ZNF574 | zinc finger protein 574 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
