telomere maintenance Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and the length of telomeric DNA. These processes includes those that shorten and lengthen the telomeric DNA sequences. (Gene Ontology, GO_0000723)
External Link http://amigo.geneontology.org/amigo/term/GO:0000723
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Genes

73 genes participating in the telomere maintenance biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ACTL6A actin-like 6A
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARTN artemin
ATM ATM serine/threonine kinase
BLM Bloom syndrome, RecQ helicase-like
CDK2 cyclin-dependent kinase 2
CTC1 CTS telomere maintenance complex component 1
DCLRE1B DNA cross-link repair 1B
DCLRE1C DNA cross-link repair 1C
DNA2 DNA replication helicase/nuclease 2
ERCC4 excision repair cross-complementation group 4
FBXO4 F-box protein 4
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
INO80 INO80 complex subunit
INO80B INO80 complex subunit B
INO80C INO80 complex subunit C
INO80D INO80 complex subunit D
INO80E INO80 complex subunit E
LRIF1 ligand dependent nuclear receptor interacting factor 1
LTO1 LTO1 maturation factor of ABCE1
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MCRS1 microspherule protein 1
MRE11 MRE11 homolog, double strand break repair nuclease
NFRKB nuclear factor related to kappaB binding protein
NHEJ1 nonhomologous end-joining factor 1
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
PARP1 poly (ADP-ribose) polymerase 1
PARP3 poly (ADP-ribose) polymerase family, member 3
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POT1 protection of telomeres 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGES3 prostaglandin E synthase 3 (cytosolic)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51D RAD51 paralog D
RECQL4 RecQ protein-like 4
RPA3 replication protein A3, 14kDa
RTEL1 regulator of telomere elongation helicase 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SHLD1 shieldin complex subunit 1
SHLD2 shieldin complex subunit 2
SHLD3 shieldin complex subunit 3
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
SMC5 structural maintenance of chromosomes 5
SMC6 structural maintenance of chromosomes 6
SP100 SP100 nuclear antigen
STN1 STN1 subunit of CST complex
TEN1 TEN1 CST complex subunit
TEP1 telomerase-associated protein 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
WRN Werner syndrome, RecQ helicase-like
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YY1 YY1 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZNF365 zinc finger protein 365
ZNF827 zinc finger protein 827
ZSCAN4 zinc finger and SCAN domain containing 4