tenoxicam-2501 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tenoxicam-2501 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADAM12 ADAM metallopeptidase domain 12
ADARB1 adenosine deaminase, RNA-specific, B1
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AIM1L absent in melanoma 1-like
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APC adenomatous polyposis coli
ARMC4 armadillo repeat containing 4
ATAT1 alpha tubulin acetyltransferase 1
ATP13A2 ATPase type 13A2
BARX1 BARX homeobox 1
BCL2L2 BCL2-like 2
BIRC7 baculoviral IAP repeat containing 7
BTD biotinidase
C1ORF105 chromosome 1 open reading frame 105
CCDC57 coiled-coil domain containing 57
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEP164 centrosomal protein 164kDa
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRAT carnitine O-acetyltransferase
CREM cAMP responsive element modulator
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCAF4 DDB1 and CUL4 associated factor 4
DGCR2 DiGeorge syndrome critical region gene 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMWD dystrophia myotonica, WD repeat containing
EFR3B EFR3 homolog B (S. cerevisiae)
EIF1 eukaryotic translation initiation factor 1
EPX eosinophil peroxidase
FAM168A family with sequence similarity 168, member A
FBXL7 F-box and leucine-rich repeat protein 7
FLOT1 flotillin 1
GOLGA2P5 golgin A2 pseudogene 5
GSPT1 G1 to S phase transition 1
HIPK3 homeodomain interacting protein kinase 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF26B kinesin family member 26B
LEFTY1 left-right determination factor 1
LOC390998 ribosomal protein L10 pseudogene
MBNL2 muscleblind-like splicing regulator 2
MEIS3P1 Meis homeobox 3 pseudogene 1
MMP3 matrix metallopeptidase 3
MTCP1 mature T-cell proliferation 1
MUC8 mucin 8
MVP major vault protein
MYBPC3 myosin binding protein C, cardiac
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP188 nucleoporin 188kDa
OMG oligodendrocyte myelin glycoprotein
OSBPL10 oxysterol binding protein-like 10
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4D phosphodiesterase 4D, cAMP-specific
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PLCL1 phospholipase C-like 1
PLSCR3 phospholipid scramblase 3
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRF1 perforin 1 (pore forming protein)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RANBP1 RAN binding protein 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUFY3 RUN and FYVE domain containing 3
SBNO2 strawberry notch homolog 2 (Drosophila)
SCN5A sodium channel, voltage gated, type V alpha subunit
SFN stratifin
SHOX2 short stature homeobox 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SPG20 spastic paraplegia 20 (Troyer syndrome)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH3 slingshot protein phosphatase 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STEAP1 six transmembrane epithelial antigen of the prostate 1
STOML1 stomatin (EPB72)-like 1
TFF2 trefoil factor 2
THSD7A thrombospondin, type I, domain containing 7A
TRIM3 tripartite motif containing 3
TSPAN9 tetraspanin 9
TULP2 tubby like protein 2
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WIZ widely interspaced zinc finger motifs
XYLB xylulokinase homolog (H. influenzae)
ZBTB17 zinc finger and BTB domain containing 17
ZBTB33 zinc finger and BTB domain containing 33
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIRE autoimmune regulator
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASGR2 asialoglycoprotein receptor 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCAS3 breast carcinoma amplified sequence 3
BPI bactericidal/permeability-increasing protein
C16ORF45 chromosome 16 open reading frame 45
C16ORF59 chromosome 16 open reading frame 59
C7ORF69 chromosome 7 open reading frame 69
CBR3 carbonyl reductase 3
CCDC186 coiled-coil domain containing 186
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CELP carboxyl ester lipase pseudogene
CEND1 cell cycle exit and neuronal differentiation 1
CENPO centromere protein O
CTSV cathepsin V
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOC2A double C2-like domains, alpha
DOK3 docking protein 3
DOK5 docking protein 5
DPY19L1P1 DPY19L1 pseudogene 1
EMILIN2 elastin microfibril interfacer 2
FBP1 fructose-1,6-bisphosphatase 1
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
FOXO4 forkhead box O4
FRMPD1 FERM and PDZ domain containing 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GALE UDP-galactose-4-epimerase
GCH1 GTP cyclohydrolase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GEMIN7 gem (nuclear organelle) associated protein 7
GIF gastric intrinsic factor (vitamin B synthesis)
GJA9 gap junction protein, alpha 9, 59kDa
GPR1 G protein-coupled receptor 1
GPR20 G protein-coupled receptor 20
GPR68 G protein-coupled receptor 68
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HIST1H2AJ histone cluster 1, H2aj
HIST1H4E histone cluster 1, H4e
HOXB9 homeobox B9
HSPB8 heat shock 22kDa protein 8
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
INCENP inner centromere protein antigens 135/155kDa
KIAA1456 KIAA1456
LRRK1 leucine-rich repeat kinase 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MORN1 MORN repeat containing 1
MRPL41 mitochondrial ribosomal protein L41
NCKAP1L NCK-associated protein 1-like
NPR3 natriuretic peptide receptor 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDLIM1 PDZ and LIM domain 1
PHACTR1 phosphatase and actin regulator 1
PNOC prepronociceptin
POM121 POM121 transmembrane nucleoporin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PQLC2 PQ loop repeat containing 2
PRDM12 PR domain containing 12
PRR7 proline rich 7 (synaptic)
RAB13 RAB13, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
REPS2 RALBP1 associated Eps domain containing 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLMO1 slowmo homolog 1 (Drosophila)
SNX29P2 sorting nexin 29 pseudogene 2
SORBS3 sorbin and SH3 domain containing 3
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TRAF1 TNF receptor-associated factor 1
TTPAL tocopherol (alpha) transfer protein-like
USP6NL USP6 N-terminal like
VASH2 vasohibin 2
VSIG10 V-set and immunoglobulin domain containing 10
XDH xanthine dehydrogenase
ZBTB16 zinc finger and BTB domain containing 16
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF234 zinc finger protein 234
ZNF37BP zinc finger protein 37B, pseudogene