tenoxicam-4182 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tenoxicam-4182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADAM29 ADAM metallopeptidase domain 29
ADGRE3 adhesion G protein-coupled receptor E3
ADGRG1 adhesion G protein-coupled receptor G1
AMBP alpha-1-microglobulin/bikunin precursor
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AQP6 aquaporin 6, kidney specific
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BHMT betaine--homocysteine S-methyltransferase
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BRSK2 BR serine/threonine kinase 2
C10ORF10 chromosome 10 open reading frame 10
C10ORF12 chromosome 10 open reading frame 12
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP4 caspase 4, apoptosis-related cysteine peptidase
CD200 CD200 molecule
CD5 CD5 molecule
CFDP1 craniofacial development protein 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CSF1 colony stimulating factor 1 (macrophage)
CTSZ cathepsin Z
DCHS2 dachsous cadherin-related 2
DCT dopachrome tautomerase
DFNB31 deafness, autosomal recessive 31
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DMPK dystrophia myotonica-protein kinase
EFR3B EFR3 homolog B (S. cerevisiae)
ELP6 elongator acetyltransferase complex subunit 6
F13A1 coagulation factor XIII, A1 polypeptide
GGT1 gamma-glutamyltransferase 1
GP2 glycoprotein 2 (zymogen granule membrane)
HAVCR1 hepatitis A virus cellular receptor 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DOB major histocompatibility complex, class II, DO beta
IL17RA interleukin 17 receptor A
IL2RA interleukin 2 receptor, alpha
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAM3 junctional adhesion molecule 3
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
KRT15 keratin 15, type I
KRT38 keratin 38, type I
LGALS13 lectin, galactoside-binding, soluble, 13
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIMCH1 LIM and calponin homology domains 1
LINC00260 long intergenic non-protein coding RNA 260
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC79999 uncharacterized LOC79999
LRRC31 leucine rich repeat containing 31
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MBD2 methyl-CpG binding domain protein 2
MC5R melanocortin 5 receptor
MIER2 mesoderm induction early response 1, family member 2
MMRN2 multimerin 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OMD osteomodulin
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PAPPA2 pappalysin 2
PCDH17 protocadherin 17
PCDHB1 protocadherin beta 1
PER1 period circadian clock 1
PODNL1 podocan-like 1
POU6F2 POU class 6 homeobox 2
PRB3 proline-rich protein BstNI subfamily 3
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN7 protein tyrosine phosphatase, non-receptor type 7
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC35G2 solute carrier family 35, member G2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNRK SNF related kinase
SOX21 SRY (sex determining region Y)-box 21
SPN sialophorin
SRCAP Snf2-related CREBBP activator protein
STIM1 stromal interaction molecule 1
TBX6 T-box 6
TDO2 tryptophan 2,3-dioxygenase
TDRD12 tudor domain containing 12
TESPA1 thymocyte expressed, positive selection associated 1
TRH thyrotropin-releasing hormone
TRIM10 tripartite motif containing 10
TRIP6 thyroid hormone receptor interactor 6
TTC39A tetratricopeptide repeat domain 39A
TYRO3 TYRO3 protein tyrosine kinase
VAV2 vav 2 guanine nucleotide exchange factor
WIPF1 WAS/WASL interacting protein family, member 1
ZER1 zyg-11 related, cell cycle regulator
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF79 zinc finger protein 79
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AIRE autoimmune regulator
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BIRC7 baculoviral IAP repeat containing 7
C10ORF95 chromosome 10 open reading frame 95
C3 complement component 3
CASC1 cancer susceptibility candidate 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CD8A CD8a molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CPB2 carboxypeptidase B2 (plasma)
CRLF1 cytokine receptor-like factor 1
CTSO cathepsin O
CUEDC1 CUE domain containing 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
DOCK3 dedicator of cytokinesis 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECM1 extracellular matrix protein 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF5A2 eukaryotic translation initiation factor 5A2
EPX eosinophil peroxidase
FAM212B family with sequence similarity 212, member B
FAM76A family with sequence similarity 76, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO4 F-box protein 4
FGL1 fibrinogen-like 1
FRMD1 FERM domain containing 1
FSTL1 follistatin-like 1
GFI1 growth factor independent 1 transcription repressor
GPR143 G protein-coupled receptor 143
GSPT2 G1 to S phase transition 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAMP hepcidin antimicrobial peptide
HDAC11 histone deacetylase 11
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HOXA4 homeobox A4
HSPB6 heat shock protein, alpha-crystallin-related, B6
INPP5J inositol polyphosphate-5-phosphatase J
IVL involucrin
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KDM5C lysine (K)-specific demethylase 5C
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0319L KIAA0319-like
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT75 keratin 75, type II
LIME1 Lck interacting transmembrane adaptor 1
LOC729164 hCG1732469
LY6G6C lymphocyte antigen 6 complex, locus G6C
MXRA8 matrix-remodelling associated 8
NNAT neuronatin
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NYNRIN NYN domain and retroviral integrase containing
ONECUT2 one cut homeobox 2
OVOL1 ovo-like zinc finger 1
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLAC4 placenta-specific 4
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLSCR4 phospholipid scramblase 4
PLXNB3 plexin B3
POM121 POM121 transmembrane nucleoporin
PQLC2 PQ loop repeat containing 2
RAB30 RAB30, member RAS oncogene family
RASIP1 Ras interacting protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SAA4 serum amyloid A4, constitutive
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC3 syndecan 3
SGK2 serum/glucocorticoid regulated kinase 2
SLC16A4 solute carrier family 16, member 4
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNCAIP synuclein, alpha interacting protein
SPINK4 serine peptidase inhibitor, Kazal type 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STMN3 stathmin-like 3
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TBKBP1 TBK1 binding protein 1
TMCC2 transmembrane and coiled-coil domain family 2
TRAIP TRAF interacting protein
TSC22D4 TSC22 domain family, member 4
VASH1 vasohibin 1
VN1R1 vomeronasal 1 receptor 1
ZNF134 zinc finger protein 134
ZNF428 zinc finger protein 428