terazosin-5831 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the terazosin-5831 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AGO3 argonaute RISC catalytic component 3
AHCYL2 adenosylhomocysteinase-like 2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARMC8 armadillo repeat containing 8
BAAT bile acid CoA:amino acid N-acyltransferase
BDKRB1 bradykinin receptor B1
BRWD1 bromodomain and WD repeat domain containing 1
C21ORF2 chromosome 21 open reading frame 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC93 coiled-coil domain containing 93
CCL21 chemokine (C-C motif) ligand 21
CCNJL cyclin J-like
CDK13 cyclin-dependent kinase 13
CFLAR CASP8 and FADD-like apoptosis regulator
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLCN7 chloride channel, voltage-sensitive 7
CLDN17 claudin 17
CLIC5 chloride intracellular channel 5
COL4A6 collagen, type IV, alpha 6
CORO2A coronin, actin binding protein, 2A
CSPP1 centrosome and spindle pole associated protein 1
CYLD cylindromatosis (turban tumor syndrome)
DCN decorin
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DTX2 deltex 2, E3 ubiquitin ligase
ELMO2 engulfment and cell motility 2
FABP3 fatty acid binding protein 3, muscle and heart
FAM120C family with sequence similarity 120C
FAM214B family with sequence similarity 214, member B
FBXO40 F-box protein 40
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR135 G protein-coupled receptor 135
GPSM3 G-protein signaling modulator 3
GSTM1 glutathione S-transferase mu 1
GTPBP4 GTP binding protein 4
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIST1H1D histone cluster 1, H1d
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HOXC10 homeobox C10
HOXD3 homeobox D3
HOXD9 homeobox D9
HSDL2 hydroxysteroid dehydrogenase like 2
HSF2BP heat shock transcription factor 2 binding protein
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL1RN interleukin 1 receptor antagonist
IQCE IQ motif containing E
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA0753 KIAA0753
KMT2A lysine (K)-specific methyltransferase 2A
KRT6B keratin 6B, type II
LUC7L LUC7-like (S. cerevisiae)
MMP13 matrix metallopeptidase 13
MPPE1 metallophosphoesterase 1
MPZ myelin protein zero
NEB nebulin
NIPAL3 NIPA-like domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NUP214 nucleoporin 214kDa
OSBPL2 oxysterol binding protein-like 2
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDLIM5 PDZ and LIM domain 5
PEX16 peroxisomal biogenesis factor 16
PKP1 plakophilin 1
PLD3 phospholipase D family, member 3
PRB1 proline-rich protein BstNI subfamily 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT2IP PRMT2 interacting protein
QPCTL glutaminyl-peptide cyclotransferase-like
RAD50 RAD50 homolog (S. cerevisiae)
RAD52 RAD52 homolog (S. cerevisiae)
RGS10 regulator of G-protein signaling 10
RGS7 regulator of G-protein signaling 7
RNF122 ring finger protein 122
SCAPER S-phase cyclin A-associated protein in the ER
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRSF7 serine/arginine-rich splicing factor 7
TFIP11 tuftelin interacting protein 11
TJAP1 tight junction associated protein 1 (peripheral)
TMCC1 transmembrane and coiled-coil domain family 1
TRIM62 tripartite motif containing 62
TSKU tsukushi, small leucine rich proteoglycan
TXK TXK tyrosine kinase
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VCAN versican
WIZ widely interspaced zinc finger motifs
YOD1 YOD1 deubiquitinase
ZNF174 zinc finger protein 174
ZNF335 zinc finger protein 335
ZNF408 zinc finger protein 408
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ANKZF1 ankyrin repeat and zinc finger domain containing 1
BAHCC1 BAH domain and coiled-coil containing 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF35 chromosome 1 open reading frame 35
CCDC88C coiled-coil domain containing 88C
CCDC94 coiled-coil domain containing 94
CDADC1 cytidine and dCMP deaminase domain containing 1
CEP112 centrosomal protein 112kDa
CFAP69 cilia and flagella associated protein 69
CHML choroideremia-like (Rab escort protein 2)
CLDN14 claudin 14
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CMTR1 cap methyltransferase 1
CNN2 calponin 2
COBL cordon-bleu WH2 repeat protein
CRYL1 crystallin, lambda 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DENND4A DENN/MADD domain containing 4A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERF Ets2 repressor factor
FAF1 Fas (TNFRSF6) associated factor 1
FBRS fibrosin
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
HIST1H2AI histone cluster 1, H2ai
HMOX1 heme oxygenase 1
INF2 inverted formin, FH2 and WH2 domain containing
ITM2C integral membrane protein 2C
KDM5C lysine (K)-specific demethylase 5C
KIAA1549L KIAA1549-like
KLHL36 kelch-like family member 36
KRT4 keratin 4, type II
LAMB2 laminin, beta 2 (laminin S)
LINC00597 long intergenic non-protein coding RNA 597
LOC100127972 uncharacterized LOC100127972
MRPS34 mitochondrial ribosomal protein S34
MXRA8 matrix-remodelling associated 8
NARFL nuclear prelamin A recognition factor-like
NECAB3 N-terminal EF-hand calcium binding protein 3
NRTN neurturin
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PADI1 peptidyl arginine deiminase, type I
PAQR6 progestin and adipoQ receptor family member VI
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PELP1 proline, glutamate and leucine rich protein 1
PLCD1 phospholipase C, delta 1
PRSS16 protease, serine, 16 (thymus)
RIN1 Ras and Rab interactor 1
RLF rearranged L-myc fusion
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SCARA3 scavenger receptor class A, member 3
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SETD6 SET domain containing 6
SKA1 spindle and kinetochore associated complex subunit 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SPAG4 sperm associated antigen 4
SPATA1 spermatogenesis associated 1
TMEM156 transmembrane protein 156
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TNK1 tyrosine kinase, non-receptor, 1
TRIM21 tripartite motif containing 21
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN12 tetraspanin 12
TSPYL2 TSPY-like 2
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEZT vezatin, adherens junctions transmembrane protein
WDR91 WD repeat domain 91
ZFP69B ZFP69 zinc finger protein B
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT3 zinc finger, matrin-type 3
ZNF189 zinc finger protein 189
ZNF212 zinc finger protein 212
ZNF37BP zinc finger protein 37B, pseudogene
ZNF747 zinc finger protein 747