terbutaline-5764 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the terbutaline-5764 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
AKAP12 A kinase (PRKA) anchor protein 12
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
ATXN2L ataxin 2-like
BCL2A1 BCL2-related protein A1
BMP2 bone morphogenetic protein 2
C14ORF93 chromosome 14 open reading frame 93
CA5B carbonic anhydrase VB, mitochondrial
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDRT1 CMT1A duplicated region transcript 1
CEMIP cell migration inducing protein, hyaluronan binding
CFP complement factor properdin
COMT catechol-O-methyltransferase
CPA3 carboxypeptidase A3 (mast cell)
CREM cAMP responsive element modulator
CRMP1 collapsin response mediator protein 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
DFNB31 deafness, autosomal recessive 31
DMBT1 deleted in malignant brain tumors 1
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP1 dual specificity phosphatase 1
E2F4 E2F transcription factor 4, p107/p130-binding
ELL elongation factor RNA polymerase II
EPAS1 endothelial PAS domain protein 1
FAM149B1 family with sequence similarity 149, member B1
FBXO40 F-box protein 40
FOXG1 forkhead box G1
FRMD4B FERM domain containing 4B
GAN gigaxonin
GBP1 guanylate binding protein 1, interferon-inducible
GPR1 G protein-coupled receptor 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HOXB2 homeobox B2
IFI44L interferon-induced protein 44-like
IL11 interleukin 11
IL1R1 interleukin 1 receptor, type I
IL33 interleukin 33
IL33R interleukin 33 receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITFG2 integrin alpha FG-GAP repeat containing 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD14 potassium channel tetramerization domain containing 14
KLF12 Kruppel-like factor 12
KLF13 Kruppel-like factor 13
KLHL25 kelch-like family member 25
KRT17 keratin 17, type I
KRT86 keratin 86, type II
MAP7 microtubule-associated protein 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAU2 MAU2 sister chromatid cohesion factor
MOCS1 molybdenum cofactor synthesis 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NF1 neurofibromin 1
NPR1 natriuretic peptide receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ONECUT2 one cut homeobox 2
PAX5 paired box 5
PDE4D phosphodiesterase 4D, cAMP-specific
PDLIM3 PDZ and LIM domain 3
PHF14 PHD finger protein 14
PIP prolactin-induced protein
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP5C protein phosphatase 5, catalytic subunit
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
R3HDM1 R3H domain containing 1
RBM17 RNA binding motif protein 17
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS4 regulator of G-protein signaling 4
RPS4Y1 ribosomal protein S4, Y-linked 1
RSU1 Ras suppressor protein 1
S100P S100 calcium binding protein P
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SMAD7 SMAD family member 7
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMOX spermine oxidase
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOSTDC1 sclerostin domain containing 1
SPAG8 sperm associated antigen 8
SRRT serrate, RNA effector molecule
STC1 stanniocalcin 1
SYT17 synaptotagmin XVII
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TGFB2 transforming growth factor, beta 2
THSD4 thrombospondin, type I, domain containing 4
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARRB2 arrestin, beta 2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASIC3 acid sensing (proton gated) ion channel 3
BEX4 brain expressed, X-linked 4
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
C1RL complement component 1, r subcomponent-like
CD82 CD82 molecule
CDK6 cyclin-dependent kinase 6
CLEC2B C-type lectin domain family 2, member B
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUSP14 dual specificity phosphatase 14
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FBRS fibrosin
FOXN2 forkhead box N2
G0S2 G0/G1 switch 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GBX2 gastrulation brain homeobox 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPATCH3 G patch domain containing 3
GPX2 glutathione peroxidase 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC5 histone deacetylase 5
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HOXA4 homeobox A4
HOXC13 homeobox C13
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IL20RA interleukin 20 receptor, alpha
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD17 potassium channel tetramerization domain containing 17
KIAA1462 KIAA1462
KIRREL kin of IRRE like (Drosophila)
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
LAMB2 laminin, beta 2 (laminin S)
LPAR6 lysophosphatidic acid receptor 6
LRP3 low density lipoprotein receptor-related protein 3
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAGEB2 melanoma antigen family B2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MFSD12 major facilitator superfamily domain containing 12
MOXD1 monooxygenase, DBH-like 1
MXD3 MAX dimerization protein 3
MYH15 myosin, heavy chain 15
MYL5 myosin, light chain 5, regulatory
NAG18 NAG18 mRNA
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPY1R neuropeptide Y receptor Y1
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P3H2 prolyl 3-hydroxylase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PER3 period circadian clock 3
PIDD1 p53-induced death domain protein 1
PLAC1 placenta-specific 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PTX3 pentraxin 3, long
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF2 ring finger protein 2
RUNX1-IT1 RUNX1 intronic transcript 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
STARD3 StAR-related lipid transfer (START) domain containing 3
SULT4A1 sulfotransferase family 4A, member 1
TBX19 T-box 19
TMEM156 transmembrane protein 156
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAF2 TNF receptor-associated factor 2
USP32 ubiquitin specific peptidase 32
WDR78 WD repeat domain 78
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZBTB6 zinc finger and BTB domain containing 6
ZFHX2 zinc finger homeobox 2
ZNF230 zinc finger protein 230
ZNF362 zinc finger protein 362
ZNF415 zinc finger protein 415
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862