terconazole-2844 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the terconazole-2844 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADAM22 ADAM metallopeptidase domain 22
AFF1 AF4/FMR2 family, member 1
ALPK1 alpha-kinase 1
ATF7IP activating transcription factor 7 interacting protein
ATM ATM serine/threonine kinase
BIN1 bridging integrator 1
BST2 bone marrow stromal cell antigen 2
C10ORF95 chromosome 10 open reading frame 95
C3ORF18 chromosome 3 open reading frame 18
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD58 CD58 molecule
CD82 CD82 molecule
COL16A1 collagen, type XVI, alpha 1
CTBP2 C-terminal binding protein 2
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DIO2 deiodinase, iodothyronine, type II
DUSP1 dual specificity phosphatase 1
ECH1 enoyl CoA hydratase 1, peroxisomal
EFNB3 ephrin-B3
EHBP1L1 EH domain binding protein 1-like 1
EML2 echinoderm microtubule associated protein like 2
ERCC4 excision repair cross-complementation group 4
FAM49B family with sequence similarity 49, member B
FZD9 frizzled class receptor 9
GAB1 GRB2-associated binding protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIPR gastric inhibitory polypeptide receptor
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPR157 G protein-coupled receptor 157
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HFE hemochromatosis
HIST1H4E histone cluster 1, H4e
HLA-C major histocompatibility complex, class I, C
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA4 homeobox A4
HSDL2 hydroxysteroid dehydrogenase like 2
IL5RA interleukin 5 receptor, alpha
ING2 inhibitor of growth family, member 2
IQSEC2 IQ motif and Sec7 domain 2
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
JUN jun proto-oncogene
KDM4B lysine (K)-specific demethylase 4B
KDM8 lysine (K)-specific demethylase 8
LPIN1 lipin 1
MED18 mediator complex subunit 18
MYL10 myosin, light chain 10, regulatory
N4BP1 NEDD4 binding protein 1
NCALD neurocalcin delta
NCR3 natural cytotoxicity triggering receptor 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPHP1 nephronophthisis 1 (juvenile)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCDH9 protocadherin 9
PCNX pecanex homolog (Drosophila)
PEX26 peroxisomal biogenesis factor 26
PLA2G5 phospholipase A2, group V
POM121 POM121 transmembrane nucleoporin
PRKCE protein kinase C, epsilon
PROM1 prominin 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RABGAP1 RAB GTPase activating protein 1
REEP1 receptor accessory protein 1
RHOBTB2 Rho-related BTB domain containing 2
RNFT1 ring finger protein, transmembrane 1
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SFXN3 sideroflexin 3
SIRT5 sirtuin 5
SLC22A17 solute carrier family 22, member 17
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMC1A structural maintenance of chromosomes 1A
SMIM14 small integral membrane protein 14
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THAP9 THAP domain containing 9
TPP1 tripeptidyl peptidase I
TRAIP TRAF interacting protein
TRIB2 tribbles pseudokinase 2
TRIM62 tripartite motif containing 62
TSPAN9 tetraspanin 9
UBE3A ubiquitin protein ligase E3A
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANXA2P3 annexin A2 pseudogene 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATG4A autophagy related 4A, cysteine peptidase
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCOR BCL6 corepressor
C14ORF132 chromosome 14 open reading frame 132
CCNJ cyclin J
CCNO cyclin O
CDR2L cerebellar degeneration-related protein 2-like
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DTWD1 DTW domain containing 1
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ENO2 enolase 2 (gamma, neuronal)
EPHX2 epoxide hydrolase 2, cytoplasmic
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155B family with sequence similarity 155, member B
FAN1 FANCD2/FANCI-associated nuclease 1
FKBP5 FK506 binding protein 5
FZD6 frizzled class receptor 6
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GK3P glycerol kinase 3 pseudogene
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPATCH3 G patch domain containing 3
HCFC2 host cell factor C2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IP6K1 inositol hexakisphosphate kinase 1
IPO8 importin 8
KIAA0232 KIAA0232
KIF18A kinesin family member 18A
KLHL2 kelch-like family member 2
KLK5 kallikrein-related peptidase 5
KRT8P12 keratin 8 pseudogene 12
LBR lamin B receptor
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MCOLN3 mucolipin 3
MDM4 MDM4, p53 regulator
MTMR6 myotubularin related protein 6
MXD3 MAX dimerization protein 3
NFS1 NFS1 cysteine desulfurase
NKAIN1 Na+/K+ transporting ATPase interacting 1
OSMR oncostatin M receptor
PHEX phosphate regulating endopeptidase homolog, X-linked
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRAF2 PRA1 domain family, member 2
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRU protein tyrosine phosphatase, receptor type, U
QSER1 glutamine and serine rich 1
RAB4B RAB4B, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIC8B RIC8 guanine nucleotide exchange factor B
RIPK4 receptor-interacting serine-threonine kinase 4
RPGR retinitis pigmentosa GTPase regulator
RPIA ribose 5-phosphate isomerase A
SAMHD1 SAM domain and HD domain 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH3GL1 SH3-domain GRB2-like 1
SIRT2 sirtuin 2
SIX1 SIX homeobox 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SUN2 Sad1 and UNC84 domain containing 2
TET3 tet methylcytosine dioxygenase 3
TLN1 talin 1
TMEM115 transmembrane protein 115
TMEM2 transmembrane protein 2
TMPRSS2 transmembrane protease, serine 2
TPST2 tyrosylprotein sulfotransferase 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC33 tetratricopeptide repeat domain 33
TXLNA taxilin alpha
USP18 ubiquitin specific peptidase 18
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WRN Werner syndrome, RecQ helicase-like
WWC2 WW and C2 domain containing 2
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZNF10 zinc finger protein 10
ZNF266 zinc finger protein 266
ZNF350 zinc finger protein 350
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573