| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the terfenadine-1381 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
| ANXA2 | annexin A2 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ATP10A | ATPase, class V, type 10A |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| AXL | AXL receptor tyrosine kinase |
| BCL3 | B-cell CLL/lymphoma 3 |
| BTG2 | BTG family, member 2 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNG2 | cyclin G2 |
| CD83 | CD83 molecule |
| CLEC7A | C-type lectin domain family 7, member A |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CSNK1D | casein kinase 1, delta |
| CTSB | cathepsin B |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DUS2 | dihydrouridine synthase 2 |
| DUSP10 | dual specificity phosphatase 10 |
| EGR2 | early growth response 2 |
| ELMO2 | engulfment and cell motility 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM134B | family with sequence similarity 134, member B |
| FCMR | Fc fragment of IgM receptor |
| FTH1 | ferritin, heavy polypeptide 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPNMB | glycoprotein (transmembrane) nmb |
| HBP1 | HMG-box transcription factor 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2BE | histone cluster 1, H2be |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| IER3 | immediate early response 3 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFI44 | interferon-induced protein 44 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL1RN | interleukin 1 receptor antagonist |
| INSIG1 | insulin induced gene 1 |
| IRF7 | interferon regulatory factor 7 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KIZ | kizuna centrosomal protein |
| KLF10 | Kruppel-like factor 10 |
| KYNU | kynureninase |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALT1 | MALT1 paracaspase |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MX1 | MX dynamin-like GTPase 1 |
| MX2 | MX dynamin-like GTPase 2 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLSCR1 | phospholipid scramblase 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| RAB8B | RAB8B, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS1 | regulator of G-protein signaling 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RHOH | ras homolog family member H |
| RNF19B | ring finger protein 19B |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEC24D | SEC24 family member D |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SMOX | spermine oxidase |
| SP110 | SP110 nuclear body protein |
| SPP1 | secreted phosphoprotein 1 |
| SQSTM1 | sequestosome 1 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| SUGP1 | SURP and G patch domain containing 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TELO2 | telomere maintenance 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TRAC | T cell receptor alpha constant |
| TRIM22 | tripartite motif containing 22 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XAF1 | XIAP associated factor 1 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ABT1 | activator of basal transcription 1 |
| ACVR2A | activin A receptor, type IIA |
| ADCK3 | aarF domain containing kinase 3 |
| ADSS | adenylosuccinate synthase |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BRD9 | bromodomain containing 9 |
| BYSL | bystin-like |
| CA2 | carbonic anhydrase II |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CORO2A | coronin, actin binding protein, 2A |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DPP3 | dipeptidyl-peptidase 3 |
| ELANE | elastase, neutrophil expressed |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EVL | Enah/Vasp-like |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FES | FES proto-oncogene, tyrosine kinase |
| FLT3 | fms-related tyrosine kinase 3 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GATAD2A | GATA zinc finger domain containing 2A |
| GCDH | glutaryl-CoA dehydrogenase |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0930 | KIAA0930 |
| LBR | lamin B receptor |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LSP1 | lymphocyte-specific protein 1 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| MLYCD | malonyl-CoA decarboxylase |
| MPO | myeloperoxidase |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYH9 | myosin, heavy chain 9, non-muscle |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUCB2 | nucleobindin 2 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PLAC8 | placenta-specific 8 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PMM2 | phosphomannomutase 2 |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POU2F1 | POU class 2 homeobox 1 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase |
| PRTN3 | proteinase 3 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| REXO2 | RNA exonuclease 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A12 | S100 calcium binding protein A12 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SLN | sarcolipin |
| SPIN1 | spindlin 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TEX40 | testis expressed 40 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBS4 | thrombospondin 4 |
| TSPAN32 | tetraspanin 32 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UNG | uracil-DNA glycosylase |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP20 | ubiquitin specific peptidase 20 |
| YY2 | YY2 transcription factor |
| ZNF408 | zinc finger protein 408 |
| ZNF529 | zinc finger protein 529 |
| ZNF536 | zinc finger protein 536 |
