| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the terfenadine-2227 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BDKRB2 | bradykinin receptor B2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CCNG2 | cyclin G2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR4 | early growth response 4 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4H | histone cluster 1, H4h |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HOXB2 | homeobox B2 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IER2 | immediate early response 2 |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LOC157562 | uncharacterized LOC157562 |
| LPIN1 | lipin 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK7 | mitogen-activated protein kinase 7 |
| MVD | mevalonate (diphospho) decarboxylase |
| NF2 | neurofibromin 2 (merlin) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RCAN1 | regulator of calcineurin 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS2 | regulator of G-protein signaling 2 |
| RND1 | Rho family GTPase 1 |
| S100A8 | S100 calcium binding protein A8 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| TEX14 | testis expressed 14 |
| TNF | tumor necrosis factor |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPP1 | tripeptidyl peptidase I |
| TRIB3 | tribbles pseudokinase 3 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C5AR2 | complement component 5a receptor 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA2 | carbonic anhydrase II |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCNE2 | cyclin E2 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDON | cell adhesion associated, oncogene regulated |
| CHST10 | carbohydrate sulfotransferase 10 |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CROT | carnitine O-octanoyltransferase |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FER | fer (fps/fes related) tyrosine kinase |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GPR27 | G protein-coupled receptor 27 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELLS | helicase, lymphoid-specific |
| HIST1H1D | histone cluster 1, H1d |
| HOXA4 | homeobox A4 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| IPO8 | importin 8 |
| IPP | intracisternal A particle-promoted polypeptide |
| KIF3A | kinesin family member 3A |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LOC257152 | uncharacterized LOC257152 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MANEA | mannosidase, endo-alpha |
| MBTD1 | mbt domain containing 1 |
| METTL8 | methyltransferase like 8 |
| MGC12488 | |
| MIS18BP1 | MIS18 binding protein 1 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MSMB | microseminoprotein, beta- |
| NIPAL2 | NIPA-like domain containing 2 |
| NPTX1 | neuronal pentraxin I |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OSMR | oncostatin M receptor |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| POLL | polymerase (DNA directed), lambda |
| PROS1 | protein S (alpha) |
| PRR14L | proline rich 14-like |
| PRR15L | proline rich 15-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB30 | RAB30, member RAS oncogene family |
| RANBP6 | RAN binding protein 6 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAB2 | stabilin 2 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STIM1 | stromal interaction molecule 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TDRD1 | tudor domain containing 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR91 | WD repeat domain 91 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZIC3 | Zic family member 3 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF74 | zinc finger protein 74 |
| ZNF770 | zinc finger protein 770 |
