| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the terfenadine-6823 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ARC | activity-regulated cytoskeleton-associated protein |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CD83 | CD83 molecule |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN1 | claudin 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ETV5 | ets variant 5 |
| FGF18 | fibroblast growth factor 18 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HMOX1 | heme oxygenase 1 |
| HRK | harakiri, BCL2 interacting protein |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JAG1 | jagged 1 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| LIN7A | lin-7 homolog A (C. elegans) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| RCAN1 | regulator of calcineurin 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RND1 | Rho family GTPase 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| TBKBP1 | TBK1 binding protein 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| B3GNT1 | |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCNE2 | cyclin E2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CENPB | centromere protein B, 80kDa |
| CFD | complement factor D (adipsin) |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENDOD1 | endonuclease domain containing 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM134B | family with sequence similarity 134, member B |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FHOD1 | formin homology 2 domain containing 1 |
| FOXI1 | forkhead box I1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GAS8 | growth arrest-specific 8 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT140 | intraflagellar transport 140 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| IPP | intracisternal A particle-promoted polypeptide |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0125 | KIAA0125 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LHX6 | LIM homeobox 6 |
| LMBR1L | limb development membrane protein 1-like |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYRM9 | LYR motif containing 9 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NHLRC2 | NHL repeat containing 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NRSN2 | neurensin 2 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHA6 | protocadherin alpha 6 |
| PGBD5 | piggyBac transposable element derived 5 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PROCR | protein C receptor, endothelial |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| STX17 | syntaxin 17 |
| TAOK1 | TAO kinase 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TRIM21 | tripartite motif containing 21 |
| TRIM66 | tripartite motif containing 66 |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR76 | WD repeat domain 76 |
| ZNF227 | zinc finger protein 227 |
| ZNF324 | zinc finger protein 324 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| ZNF74 | zinc finger protein 74 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
