terguride-3096 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the terguride-3096 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALOX5 arachidonate 5-lipoxygenase
AP3B2 adaptor-related protein complex 3, beta 2 subunit
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
BGN biglycan
C1ORF68 chromosome 1 open reading frame 68
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASZ1 castor zinc finger 1
CBR3 carbonyl reductase 3
CCL27 chemokine (C-C motif) ligand 27
CDC14B cell division cycle 14B
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDON cell adhesion associated, oncogene regulated
CLPS colipase, pancreatic
CLTA clathrin, light chain A
CNTNAP1 contactin associated protein 1
COL8A1 collagen, type VIII, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CREM cAMP responsive element modulator
CRH corticotropin releasing hormone
CTTN cortactin
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDN dendrin
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DOK3 docking protein 3
EFNA3 ephrin-A3
EPS8L1 EPS8-like 1
ETV7 ets variant 7
FAM131A family with sequence similarity 131, member A
FAXDC2 fatty acid hydroxylase domain containing 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGD1 FYVE, RhoGEF and PH domain containing 1
FST follistatin
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
FXYD3 FXYD domain containing ion transport regulator 3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLDC glycine dehydrogenase (decarboxylating)
GRM4 glutamate receptor, metabotropic 4
GYPB glycophorin B (MNS blood group)
HEXIM1 hexamethylene bis-acetamide inducible 1
HOXB7 homeobox B7
ICOSLG inducible T-cell co-stimulator ligand
IFITM1 interferon induced transmembrane protein 1
IZUMO4 IZUMO family member 4
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK1 potassium channel, two pore domain subfamily K, member 1
KRT17 keratin 17, type I
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
LRRC1 leucine rich repeat containing 1
MAP4 microtubule-associated protein 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM3AP minichromosome maintenance complex component 3 associated protein
MPZL1 myelin protein zero-like 1
MXD4 MAX dimerization protein 4
MYCNOS MYCN opposite strand
NCR2 natural cytotoxicity triggering receptor 2
NOP16 NOP16 nucleolar protein
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTF3 neurotrophin 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PALLD palladin, cytoskeletal associated protein
PCBP4 poly(rC) binding protein 4
PEX16 peroxisomal biogenesis factor 16
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLSCR3 phospholipid scramblase 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POU2F2 POU class 2 homeobox 2
POU2F3 POU class 2 homeobox 3
PPARA peroxisome proliferator-activated receptor alpha
RAD52 RAD52 homolog (S. cerevisiae)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RGS11 regulator of G-protein signaling 11
SCLY selenocysteine lyase
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIX1 SIX homeobox 1
SLC22A17 solute carrier family 22, member 17
SLMO1 slowmo homolog 1 (Drosophila)
SLN sarcolipin
SMTN smoothelin
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPATA2L spermatogenesis associated 2-like
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TESK1 testis-specific kinase 1
TGFB1 transforming growth factor, beta 1
TNK2 tyrosine kinase, non-receptor, 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ALPK1 alpha-kinase 1
ASPN asporin
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG2B autophagy related 2B
BCL2L2 BCL2-like 2
BIRC3 baculoviral IAP repeat containing 3
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF30 chromosome 11 open reading frame 30
C14ORF159 chromosome 14 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
C21ORF91 chromosome 21 open reading frame 91
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CBX4 chromobox homolog 4
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD1D CD1d molecule
CD300C CD300c molecule
CHPF chondroitin polymerizing factor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTLN centlein, centrosomal protein
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
DCAF17 DDB1 and CUL4 associated factor 17
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ERCC2 excision repair cross-complementation group 2
FAM50B family with sequence similarity 50, member B
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FOXO4 forkhead box O4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAMT guanidinoacetate N-methyltransferase
GPR22 G protein-coupled receptor 22
GSTA4 glutathione S-transferase alpha 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BI histone cluster 1, H2bi
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL12B interleukin 12B
IL18 interleukin 18
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA0319L KIAA0319-like
KIF24 kinesin family member 24
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LY6E lymphocyte antigen 6 complex, locus E
MBIP MAP3K12 binding inhibitory protein 1
MBNL3 muscleblind-like splicing regulator 3
MEFV Mediterranean fever
MKRN3 makorin ring finger protein 3
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MTMR12 myotubularin related protein 12
NDE1 nudE neurodevelopment protein 1
NINJ2 ninjurin 2
NLK nemo-like kinase
NOD2 nucleotide-binding oligomerization domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NT5C 5', 3'-nucleotidase, cytosolic
OCEL1 occludin/ELL domain containing 1
PANX1 pannexin 1
PARG poly (ADP-ribose) glycohydrolase
PIAS3 protein inhibitor of activated STAT, 3
PMCH pro-melanin-concentrating hormone
PROS1 protein S (alpha)
RBM42 RNA binding motif protein 42
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC16A4 solute carrier family 16, member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC35E3 solute carrier family 35, member E3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SOCS6 suppressor of cytokine signaling 6
SPATA1 spermatogenesis associated 1
SPON2 spondin 2, extracellular matrix protein
ST7L suppression of tumorigenicity 7 like
STX17 syntaxin 17
SUOX sulfite oxidase
TAPBPL TAP binding protein-like
THEM6 thioesterase superfamily member 6
TMEM156 transmembrane protein 156
TMEM19 transmembrane protein 19
TMOD3 tropomodulin 3 (ubiquitous)
TWSG1 twisted gastrulation BMP signaling modulator 1
VN1R1 vomeronasal 1 receptor 1
VNN1 vanin 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR33 WD repeat domain 33
ZDHHC24 zinc finger, DHHC-type containing 24
ZMAT5 zinc finger, matrin-type 5
ZNF197 zinc finger protein 197
ZNF254 zinc finger protein 254
ZNF350 zinc finger protein 350
ZNF606 zinc finger protein 606
ZNF667 zinc finger protein 667