terguride-5400 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the terguride-5400 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AHI1 Abelson helper integration site 1
AK1 adenylate kinase 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOL6 apolipoprotein L, 6
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
BGN biglycan
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD80 CD80 molecule
CD83 CD83 molecule
CDON cell adhesion associated, oncogene regulated
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CEP164 centrosomal protein 164kDa
CGA glycoprotein hormones, alpha polypeptide
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNTFR ciliary neurotrophic factor receptor
COL9A3 collagen, type IX, alpha 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CREBZF CREB/ATF bZIP transcription factor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAPK2 death-associated protein kinase 2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DFNB31 deafness, autosomal recessive 31
DHODH dihydroorotate dehydrogenase (quinone)
DOCK3 dedicator of cytokinesis 3
EFNB3 ephrin-B3
EHBP1L1 EH domain binding protein 1-like 1
EPOR erythropoietin receptor
EXT1 exostosin glycosyltransferase 1
FBXL7 F-box and leucine-rich repeat protein 7
FGB fibrinogen beta chain
FN1 fibronectin 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GEM GTP binding protein overexpressed in skeletal muscle
GJA4 gap junction protein, alpha 4, 37kDa
GPNMB glycoprotein (transmembrane) nmb
GPR137 G protein-coupled receptor 137
GSAP gamma-secretase activating protein
HCFC1 host cell factor C1
HGD homogentisate 1,2-dioxygenase
HIPK3 homeodomain interacting protein kinase 3
HPX hemopexin
IFNW1 interferon, omega 1
IGFBP5 insulin-like growth factor binding protein 5
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBE inhibin, beta E
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
LDLR low density lipoprotein receptor
LIN7B lin-7 homolog B (C. elegans)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOB monoamine oxidase B
MAP2K5 mitogen-activated protein kinase kinase 5
MEGF6 multiple EGF-like-domains 6
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NEUROD1 neuronal differentiation 1
NKX6-1 NK6 homeobox 1
NMT1 N-myristoyltransferase 1
NPFF neuropeptide FF-amide peptide precursor
OCLM oculomedin
OGDHL oxoglutarate dehydrogenase-like
OPCML opioid binding protein/cell adhesion molecule-like
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAC1 placenta-specific 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PML promyelocytic leukemia
POLM polymerase (DNA directed), mu
PRB4 proline-rich protein BstNI subfamily 4
RBM12B-AS1 RBM12B antisense RNA 1
RPL23AP53 ribosomal protein L23a pseudogene 53
RUNX1 runt-related transcription factor 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SYN2 synapsin II
SYT5 synaptotagmin V
TCP10 t-complex 10
TCP11L1 t-complex 11, testis-specific-like 1
THRA thyroid hormone receptor, alpha
TMC6 transmembrane channel-like 6
TMEM246 transmembrane protein 246
TP53I11 tumor protein p53 inducible protein 11
TTC9 tetratricopeptide repeat domain 9
USB1 U6 snRNA biogenesis 1
WDFY3 WD repeat and FYVE domain containing 3
WIZ widely interspaced zinc finger motifs
ZNF280A zinc finger protein 280A
ZNF41 zinc finger protein 41

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
AHCYL2 adenosylhomocysteinase-like 2
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANXA1 annexin A1
APOLD1 apolipoprotein L domain containing 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BST2 bone marrow stromal cell antigen 2
C19ORF73 chromosome 19 open reading frame 73
C7ORF43 chromosome 7 open reading frame 43
CCDC186 coiled-coil domain containing 186
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CIDEC cell death-inducing DFFA-like effector c
CLIC2 chloride intracellular channel 2
CLSTN2 calsyntenin 2
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTAGE9 CTAGE family, member 9
CUEDC1 CUE domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
F2R coagulation factor II (thrombin) receptor
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GNL1 guanine nucleotide binding protein-like 1
HIST1H1D histone cluster 1, H1d
HOXC10 homeobox C10
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IPO8 importin 8
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLF7 Kruppel-like factor 7 (ubiquitous)
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LRP2 low density lipoprotein receptor-related protein 2
LRRC20 leucine rich repeat containing 20
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
METTL16 methyltransferase like 16
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTERF4 mitochondrial transcription termination factor 4
NAT6 N-acetyltransferase 6 (GCN5-related)
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
PAIP2B poly(A) binding protein interacting protein 2B
PGR progesterone receptor
PRODH proline dehydrogenase (oxidase) 1
PROS1 protein S (alpha)
PYCRL pyrroline-5-carboxylate reductase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMIM14 small integral membrane protein 14
SPINK5 serine peptidase inhibitor, Kazal type 5
STRN striatin, calmodulin binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TET3 tet methylcytosine dioxygenase 3
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM183A transmembrane protein 183A
TRAIP TRAF interacting protein
TTC30A tetratricopeptide repeat domain 30A
TTC33 tetratricopeptide repeat domain 33
TTLL1 tubulin tyrosine ligase-like family member 1
UBQLN4 ubiquilin 4
VASH2 vasohibin 2
WFDC2 WAP four-disulfide core domain 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF408 zinc finger protein 408
ZNF639 zinc finger protein 639
ZNF804A zinc finger protein 804A