terguride-5694 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the terguride-5694 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADCY1 adenylate cyclase 1 (brain)
ADGRA2 adhesion G protein-coupled receptor A2
AGO4 argonaute RISC catalytic component 4
AJAP1 adherens junctions associated protein 1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CATSPERB catsper channel auxiliary subunit beta
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC30 coiled-coil domain containing 30
CD40LG CD40 ligand
CD5 CD5 molecule
CD72 CD72 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEP250 centrosomal protein 250kDa
CLEC5A C-type lectin domain family 5, member A
COL1A1 collagen, type I, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CPQ carboxypeptidase Q
CYHR1 cysteine/histidine-rich 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DICER1 dicer 1, ribonuclease type III
DISC1 disrupted in schizophrenia 1
DOCK9 dedicator of cytokinesis 9
DTNB dystrobrevin, beta
EDDM3A epididymal protein 3A
EFHC2 EF-hand domain (C-terminal) containing 2
ERAP1 endoplasmic reticulum aminopeptidase 1
EXD3 exonuclease 3'-5' domain containing 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GIMAP6 GTPase, IMAP family member 6
GPR52 G protein-coupled receptor 52
GRM8 glutamate receptor, metabotropic 8
HIF3A hypoxia inducible factor 3, alpha subunit
HIST1H2BN histone cluster 1, H2bn
HIST1H4G histone cluster 1, H4g
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA7 homeobox A7
HOXB9 homeobox B9
IGF2-AS IGF2 antisense RNA
IL17RA interleukin 17 receptor A
IL1RAP interleukin 1 receptor accessory protein
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KLF12 Kruppel-like factor 12
KPNA5 karyopherin alpha 5 (importin alpha 6)
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRP12 low density lipoprotein receptor-related protein 12
LY9 lymphocyte antigen 9
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MALL mal, T-cell differentiation protein-like
MATN3 matrilin 3
MOBP myelin-associated oligodendrocyte basic protein
MUC5B mucin 5B, oligomeric mucus/gel-forming
NFX1 nuclear transcription factor, X-box binding 1
NHLH2 nescient helix loop helix 2
NOL10 nucleolar protein 10
NOVA2 neuro-oncological ventral antigen 2
NPR1 natriuretic peptide receptor 1
NTN3 netrin 3
PADI3 peptidyl arginine deiminase, type III
PCDHGA8 protocadherin gamma subfamily A, 8
PDPN podoplanin
PEAK1 pseudopodium-enriched atypical kinase 1
PLCD1 phospholipase C, delta 1
PLXNB3 plexin B3
PPARA peroxisome proliferator-activated receptor alpha
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PQLC3 PQ loop repeat containing 3
PRM2 protamine 2
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRO protein tyrosine phosphatase, receptor type, O
RAP2A RAP2A, member of RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS7 regulator of G-protein signaling 7
RND1 Rho family GTPase 1
SGCE sarcoglycan, epsilon
SIGLEC6 sialic acid binding Ig-like lectin 6
SKAP1 src kinase associated phosphoprotein 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SRCAP Snf2-related CREBBP activator protein
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TAL1 T-cell acute lymphocytic leukemia 1
TCF4 transcription factor 4
TEX15 testis expressed 15
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TPSG1 tryptase gamma 1
TSPAN2 tetraspanin 2
UBE3A ubiquitin protein ligase E3A
UBXN1 UBX domain protein 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACIN1 apoptotic chromatin condensation inducer 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARRB1 arrestin, beta 1
BAHCC1 BAH domain and coiled-coil containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BPGM 2,3-bisphosphoglycerate mutase
C17ORF80 chromosome 17 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CFAP44 cilia and flagella associated protein 44
CLCN2 chloride channel, voltage-sensitive 2
CLDN1 claudin 1
CLSPN claspin
CTC1 CTS telomere maintenance complex component 1
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSPP dentin sialophosphoprotein
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESRP2 epithelial splicing regulatory protein 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GJA1 gap junction protein, alpha 1, 43kDa
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IFT54 intraflagellar transport 54
IL15RA interleukin 15 receptor, alpha
KLF3 Kruppel-like factor 3 (basic)
LMBR1L limb development membrane protein 1-like
LRRC20 leucine rich repeat containing 20
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP3 latent transforming growth factor beta binding protein 3
MANBA mannosidase, beta A, lysosomal
MAP9 microtubule-associated protein 9
MCRS1 microspherule protein 1
MDM4 MDM4, p53 regulator
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF1 mitochondrial transcription termination factor 1
MYL5 myosin, light chain 5, regulatory
OCEL1 occludin/ELL domain containing 1
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OXR1 oxidation resistance 1
PACS1 phosphofurin acidic cluster sorting protein 1
PCBP4 poly(rC) binding protein 4
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PELI1 pellino E3 ubiquitin protein ligase 1
PKN1 protein kinase N1
PLA2G10 phospholipase A2, group X
PLXNA3 plexin A3
PNKP polynucleotide kinase 3'-phosphatase
POM121 POM121 transmembrane nucleoporin
PPOX protoporphyrinogen oxidase
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RANGRF RAN guanine nucleotide release factor
RCAN3 RCAN family member 3
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
S100A2 S100 calcium binding protein A2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3 stromal antigen 3
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBC1D17 TBC1 domain family, member 17
TICAM1 toll-like receptor adaptor molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM19 transmembrane protein 19
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAF2 TNF receptor-associated factor 2
TRAIP TRAF interacting protein
TRAPPC2 trafficking protein particle complex 2
TREM1 triggering receptor expressed on myeloid cells 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBXN8 UBX domain protein 8
USP18 ubiquitin specific peptidase 18
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
XYLT2 xylosyltransferase II
ZNF226 zinc finger protein 226
ZNF586 zinc finger protein 586
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN26 zinc finger and SCAN domain containing 26