terguride-6473 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the terguride-6473 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRA1A adrenoceptor alpha 1A
ALLC allantoicase
AMPD1 adenosine monophosphate deaminase 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C1ORF105 chromosome 1 open reading frame 105
C8A complement component 8, alpha polypeptide
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK3 cyclin-dependent kinase 3
CHI3L2 chitinase 3-like 2
CLEC7A C-type lectin domain family 7, member A
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DFNB31 deafness, autosomal recessive 31
DIO2 deiodinase, iodothyronine, type II
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUSP1 dual specificity phosphatase 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDRF1 erythroid differentiation regulatory factor 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EMP1 epithelial membrane protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERO1LB ERO1-like beta (S. cerevisiae)
ESR1 estrogen receptor 1
EXPH5 exophilin 5
FADS2 fatty acid desaturase 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FZD1 frizzled class receptor 1
GFI1 growth factor independent 1 transcription repressor
GOLGA8A golgin A8 family, member A
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPM6B glycoprotein M6B
GPR1 G protein-coupled receptor 1
GTPBP1 GTP binding protein 1
HIST1H2AB histone cluster 1, H2ab
HNF1A HNF1 homeobox A
IFNA6 interferon, alpha 6
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL18 interleukin 18
IL36RN interleukin 36 receptor antagonist
ING1 inhibitor of growth family, member 1
IRF4 interferon regulatory factor 4
ITGB4 integrin, beta 4
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLK13 kallikrein-related peptidase 13
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIN7A lin-7 homolog A (C. elegans)
LMOD1 leiomodin 1 (smooth muscle)
MBD1 methyl-CpG binding domain protein 1
MEFV Mediterranean fever
MGC2889 uncharacterized protein MGC2889
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MST1 macrophage stimulating 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MXD4 MAX dimerization protein 4
NCKIPSD NCK interacting protein with SH3 domain
NFIB nuclear factor I/B
NKX3-2 NK3 homeobox 2
OR2B2 olfactory receptor, family 2, subfamily B, member 2
PAWR PRKC, apoptosis, WT1, regulator
PCDHA5 protocadherin alpha 5
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PICALM phosphatidylinositol binding clathrin assembly protein
PMFBP1 polyamine modulated factor 1 binding protein 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARA retinoic acid receptor, alpha
RNF122 ring finger protein 122
RTEL1 regulator of telomere elongation helicase 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SGCE sarcoglycan, epsilon
SNX13 sorting nexin 13
SOS1 son of sevenless homolog 1 (Drosophila)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAOK2 TAO kinase 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TONSL tonsoku-like, DNA repair protein
TRIM2 tripartite motif containing 2
TRIM29 tripartite motif containing 29
TSKS testis-specific serine kinase substrate
UNC5B unc-5 homolog B (C. elegans)
WAS Wiskott-Aldrich syndrome
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM15 ADAM metallopeptidase domain 15
AFAP1 actin filament associated protein 1
ARMC6 armadillo repeat containing 6
ASPN asporin
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C7ORF43 chromosome 7 open reading frame 43
CD3D CD3d molecule, delta (CD3-TCR complex)
CGA glycoprotein hormones, alpha polypeptide
CLCN6 chloride channel, voltage-sensitive 6
CLDN17 claudin 17
CLEC16A C-type lectin domain family 16, member A
CLIC2 chloride intracellular channel 2
CLSPN claspin
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DOK5 docking protein 5
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FURIN furin (paired basic amino acid cleaving enzyme)
GALK1 galactokinase 1
GLI3 GLI family zinc finger 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRPR gastrin-releasing peptide receptor
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H3I histone cluster 1, H3i
HOXC10 homeobox C10
INO80D INO80 complex subunit D
IPO8 importin 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0125 KIAA0125
KIF13B kinesin family member 13B
KRT13 keratin 13, type I
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MICALL2 MICAL-like 2
MTERF4 mitochondrial transcription termination factor 4
MXD3 MAX dimerization protein 3
NELL2 NEL-like 2 (chicken)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRSN2 neurensin 2
OLFML2A olfactomedin-like 2A
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PADI1 peptidyl arginine deiminase, type I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRDM14 PR domain containing 14
PRICKLE3 prickle homolog 3 (Drosophila)
PRR7 proline rich 7 (synaptic)
PRSS50 protease, serine, 50
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFRP5 secreted frizzled-related protein 5
SLC12A9 solute carrier family 12, member 9
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STRA6 stimulated by retinoic acid 6
SUGP1 SURP and G patch domain containing 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TDRD7 tudor domain containing 7
TICAM1 toll-like receptor adaptor molecule 1
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TMPRSS4 transmembrane protease, serine 4
TRAF2 TNF receptor-associated factor 2
TTLL1 tubulin tyrosine ligase-like family member 1
UBIAD1 UbiA prenyltransferase domain containing 1
UPP1 uridine phosphorylase 1
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF204P zinc finger protein 204, pseudogene
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480
ZNF506 zinc finger protein 506
ZNF586 zinc finger protein 586
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747