| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the terguride-6473 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA1A | adrenoceptor alpha 1A |
| ALLC | allantoicase |
| AMPD1 | adenosine monophosphate deaminase 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C8A | complement component 8, alpha polypeptide |
| CD34 | CD34 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CD58 | CD58 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK3 | cyclin-dependent kinase 3 |
| CHI3L2 | chitinase 3-like 2 |
| CLEC7A | C-type lectin domain family 7, member A |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DFNB31 | deafness, autosomal recessive 31 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DUSP1 | dual specificity phosphatase 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMP1 | epithelial membrane protein 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ESR1 | estrogen receptor 1 |
| EXPH5 | exophilin 5 |
| FADS2 | fatty acid desaturase 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FZD1 | frizzled class receptor 1 |
| GFI1 | growth factor independent 1 transcription repressor |
| GOLGA8A | golgin A8 family, member A |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPM6B | glycoprotein M6B |
| GPR1 | G protein-coupled receptor 1 |
| GTPBP1 | GTP binding protein 1 |
| HIST1H2AB | histone cluster 1, H2ab |
| HNF1A | HNF1 homeobox A |
| IFNA6 | interferon, alpha 6 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL18 | interleukin 18 |
| IL36RN | interleukin 36 receptor antagonist |
| ING1 | inhibitor of growth family, member 1 |
| IRF4 | interferon regulatory factor 4 |
| ITGB4 | integrin, beta 4 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KLK13 | kallikrein-related peptidase 13 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MBD1 | methyl-CpG binding domain protein 1 |
| MEFV | Mediterranean fever |
| MGC2889 | uncharacterized protein MGC2889 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MST1 | macrophage stimulating 1 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MXD4 | MAX dimerization protein 4 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NFIB | nuclear factor I/B |
| NKX3-2 | NK3 homeobox 2 |
| OR2B2 | olfactory receptor, family 2, subfamily B, member 2 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PCDHA5 | protocadherin alpha 5 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RARA | retinoic acid receptor, alpha |
| RNF122 | ring finger protein 122 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SGCE | sarcoglycan, epsilon |
| SNX13 | sorting nexin 13 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TAOK2 | TAO kinase 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TONSL | tonsoku-like, DNA repair protein |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TSKS | testis-specific serine kinase substrate |
| UNC5B | unc-5 homolog B (C. elegans) |
| WAS | Wiskott-Aldrich syndrome |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AFAP1 | actin filament associated protein 1 |
| ARMC6 | armadillo repeat containing 6 |
| ASPN | asporin |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN17 | claudin 17 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLIC2 | chloride intracellular channel 2 |
| CLSPN | claspin |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DOK5 | docking protein 5 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM131A | family with sequence similarity 131, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GALK1 | galactokinase 1 |
| GLI3 | GLI family zinc finger 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRPR | gastrin-releasing peptide receptor |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H3I | histone cluster 1, H3i |
| HOXC10 | homeobox C10 |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0125 | KIAA0125 |
| KIF13B | kinesin family member 13B |
| KRT13 | keratin 13, type I |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MICALL2 | MICAL-like 2 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MXD3 | MAX dimerization protein 3 |
| NELL2 | NEL-like 2 (chicken) |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NRSN2 | neurensin 2 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRDM14 | PR domain containing 14 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR7 | proline rich 7 (synaptic) |
| PRSS50 | protease, serine, 50 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| STRA6 | stimulated by retinoic acid 6 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TDRD7 | tudor domain containing 7 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMC5 | transmembrane channel-like 5 |
| TMEM212 | transmembrane protein 212 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRAF2 | TNF receptor-associated factor 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UPP1 | uridine phosphorylase 1 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF506 | zinc finger protein 506 |
| ZNF586 | zinc finger protein 586 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |