| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the testosterone-5271 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADORA1 | adenosine A1 receptor |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAX | BCL2-associated X protein |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| BCL6 | B-cell CLL/lymphoma 6 |
| BMP1 | bone morphogenetic protein 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CD22 | CD22 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD5 | CD5 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CPM | carboxypeptidase M |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUEDC1 | CUE domain containing 1 |
| DCN | decorin |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EHD2 | EH-domain containing 2 |
| ETV5 | ets variant 5 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATAD2A | GATA zinc finger domain containing 2A |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HDLBP | high density lipoprotein binding protein |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HMOX1 | heme oxygenase 1 |
| HRH2 | histamine receptor H2 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL24 | interleukin 24 |
| INHBE | inhibin, beta E |
| INO80D | INO80 complex subunit D |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRS2 | insulin receptor substrate 2 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0125 | KIAA0125 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED16 | mediator complex subunit 16 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAV2 | neuron navigator 2 |
| NF1 | neurofibromin 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPR3 | natriuretic peptide receptor 3 |
| OLFML2A | olfactomedin-like 2A |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGES | prostaglandin E synthase |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| SDC3 | syndecan 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STAB2 | stabilin 2 |
| STK16 | serine/threonine kinase 16 |
| TAT | tyrosine aminotransferase |
| TBC1D2 | TBC1 domain family, member 2 |
| TCF20 | transcription factor 20 (AR1) |
| THY1 | Thy-1 cell surface antigen |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TSKS | testis-specific serine kinase substrate |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBXN1 | UBX domain protein 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP2 | ubiquitin specific peptidase 2 |
| WDR55 | WD repeat domain 55 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZNF428 | zinc finger protein 428 |
| ZNF516 | zinc finger protein 516 |
| ZNF76 | zinc finger protein 76 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADCY7 | adenylate cyclase 7 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARMC4 | armadillo repeat containing 4 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BAG4 | BCL2-associated athanogene 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC68 | coiled-coil domain containing 68 |
| CEP295 | centrosomal protein 295kDa |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DRD1 | dopamine receptor D1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FER | fer (fps/fes related) tyrosine kinase |
| FLCN | folliculin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPATCH2L | G patch domain containing 2-like |
| GPR1 | G protein-coupled receptor 1 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4E | histone cluster 1, H4e |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MBTD1 | mbt domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP2 | matrix metallopeptidase 2 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NEK11 | NIMA-related kinase 11 |
| NLRX1 | NLR family member X1 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDHA9 | protocadherin alpha 9 |
| PDE12 | phosphodiesterase 12 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| RAB3A | RAB3A, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RIN1 | Ras and Rab interactor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TCTN1 | tectonic family member 1 |
| TEP1 | telomerase-associated protein 1 |
| TMEM19 | transmembrane protein 19 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| YY2 | YY2 transcription factor |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
| ZNF747 | zinc finger protein 747 |