testosterone-5271 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the testosterone-5271 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA1 adenosine A1 receptor
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARHGAP26 Rho GTPase activating protein 26
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BAX BCL2-associated X protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BMP1 bone morphogenetic protein 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD22 CD22 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD5 CD5 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CPM carboxypeptidase M
CTNS cystinosin, lysosomal cystine transporter
CUEDC1 CUE domain containing 1
DCN decorin
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFR3B EFR3 homolog B (S. cerevisiae)
EGR1 early growth response 1
EGR3 early growth response 3
EHD2 EH-domain containing 2
ETV5 ets variant 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GADD45B growth arrest and DNA-damage-inducible, beta
GATAD2A GATA zinc finger domain containing 2A
GJA4 gap junction protein, alpha 4, 37kDa
GREB1 growth regulation by estrogen in breast cancer 1
HDLBP high density lipoprotein binding protein
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HMOX1 heme oxygenase 1
HRH2 histamine receptor H2
HSPG2 heparan sulfate proteoglycan 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL24 interleukin 24
INHBE inhibin, beta E
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRS2 insulin receptor substrate 2
KAT6A K(lysine) acetyltransferase 6A
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
KIAA0125 KIAA0125
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPAR4 lysophosphatidic acid receptor 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MED16 mediator complex subunit 16
MPL MPL proto-oncogene, thrombopoietin receptor
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAV2 neuron navigator 2
NF1 neurofibromin 1
NPM3 nucleophosmin/nucleoplasmin 3
NPR3 natriuretic peptide receptor 3
OLFML2A olfactomedin-like 2A
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB1 proline-rich protein BstNI subfamily 1
PTCRA pre T-cell antigen receptor alpha
PTGES prostaglandin E synthase
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PVT1 Pvt1 oncogene (non-protein coding)
RAB6B RAB6B, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BP2 SH3-domain binding protein 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35E2 solute carrier family 35, member E2
SNX29P2 sorting nexin 29 pseudogene 2
SOX9 SRY (sex determining region Y)-box 9
STAB2 stabilin 2
STK16 serine/threonine kinase 16
TAT tyrosine aminotransferase
TBC1D2 TBC1 domain family, member 2
TCF20 transcription factor 20 (AR1)
THY1 Thy-1 cell surface antigen
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TSKS testis-specific serine kinase substrate
TTC38 tetratricopeptide repeat domain 38
UBXN1 UBX domain protein 1
UNC119 unc-119 homolog (C. elegans)
USP2 ubiquitin specific peptidase 2
WDR55 WD repeat domain 55
XIST X inactive specific transcript (non-protein coding)
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF76 zinc finger protein 76
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY7 adenylate cyclase 7
ADTRP androgen-dependent TFPI-regulating protein
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARMC4 armadillo repeat containing 4
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BAG4 BCL2-associated athanogene 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC132 coiled-coil domain containing 132
CCDC68 coiled-coil domain containing 68
CEP295 centrosomal protein 295kDa
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DPY19L1P1 DPY19L1 pseudogene 1
DRD1 dopamine receptor D1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXW12 F-box and WD repeat domain containing 12
FER fer (fps/fes related) tyrosine kinase
FLCN folliculin
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPATCH2L G patch domain containing 2-like
GPR1 G protein-coupled receptor 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H4E histone cluster 1, H4e
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA1L heat shock 70kDa protein 1-like
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
KCNK12 potassium channel, two pore domain subfamily K, member 12
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC37A3 leucine rich repeat containing 37, member A3
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MMP2 matrix metallopeptidase 2
MRPL41 mitochondrial ribosomal protein L41
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NEK11 NIMA-related kinase 11
NLRX1 NLR family member X1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NT5E 5'-nucleotidase, ecto (CD73)
NXPE3 neurexophilin and PC-esterase domain family, member 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PADI1 peptidyl arginine deiminase, type I
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHA9 protocadherin alpha 9
PDE12 phosphodiesterase 12
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
RAB3A RAB3A, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SLC22A14 solute carrier family 22, member 14
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLIT2 slit homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STARD5 StAR-related lipid transfer (START) domain containing 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
TMEM19 transmembrane protein 19
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
VEZT vezatin, adherens junctions transmembrane protein
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZFHX4 zinc finger homeobox 4
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF747 zinc finger protein 747