testosterone-5636 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the testosterone-5636 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AEBP1 AE binding protein 1
AIM1L absent in melanoma 1-like
ALDOB aldolase B, fructose-bisphosphate
ANGPTL2 angiopoietin-like 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPN asporin
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
C1QB complement component 1, q subcomponent, B chain
C9ORF16 chromosome 9 open reading frame 16
CALCR calcitonin receptor
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK19 cyclin-dependent kinase 19
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CLDN17 claudin 17
CRMP1 collapsin response mediator protein 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EGR2 early growth response 2
EGR3 early growth response 3
ESR1 estrogen receptor 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FLRT1 fibronectin leucine rich transmembrane protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FSTL3 follistatin-like 3 (secreted glycoprotein)
GOLGA8A golgin A8 family, member A
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSTA3 glutathione S-transferase alpha 3
GSTTP1 glutathione S-transferase theta pseudogene 1
GYPB glycophorin B (MNS blood group)
HGD homogentisate 1,2-dioxygenase
HIPK3 homeodomain interacting protein kinase 3
HIST1H3A histone cluster 1, H3a
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLF hepatic leukemia factor
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGFBP5 insulin-like growth factor binding protein 5
IL21 interleukin 21
INHBE inhibin, beta E
ITM2C integral membrane protein 2C
KRT9 keratin 9, type I
LAMB4 laminin, beta 4
LAMC2 laminin, gamma 2
LAMP1 lysosomal-associated membrane protein 1
LARP6 La ribonucleoprotein domain family, member 6
LINC00302 long intergenic non-protein coding RNA 302
LRRC40 leucine rich repeat containing 40
LRRC8B leucine rich repeat containing 8 family, member B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MMP11 matrix metallopeptidase 11
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPZ myelin protein zero
MUC3B mucin 3B, cell surface associated
MYBPC3 myosin binding protein C, cardiac
MYO9B myosin IXB
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NKX6-1 NK6 homeobox 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCG1 phospholipase C, gamma 1
PLK3 polo-like kinase 3
PLSCR2 phospholipid scramblase 2
PRR34 proline rich 34
PSAT1 phosphoserine aminotransferase 1
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RNASE4 ribonuclease, RNase A family, 4
SCN10A sodium channel, voltage gated, type X alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SELPLG selectin P ligand
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNTG1 syntrophin, gamma 1
SPARCL1 SPARC-like 1 (hevin)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR2B small proline-rich protein 2B
STAC SH3 and cysteine rich domain
STK11 serine/threonine kinase 11
SYN2 synapsin II
TBX2 T-box 2
TEX41 testis expressed 41 (non-protein coding)
TGFB2 transforming growth factor, beta 2
UBOX5 U-box domain containing 5
UCN urocortin
WSCD1 WSC domain containing 1
ZFP64 ZFP64 zinc finger protein
ZNF277 zinc finger protein 277
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTL8 actin-like 8
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARPIN actin-related protein 2/3 complex inhibitor
ARSB arylsulfatase B
ASAP1-IT1 ASAP1 intronic transcript 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAG4 BCL2-associated athanogene 4
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BPGM 2,3-bisphosphoglycerate mutase
C11ORF63 chromosome 11 open reading frame 63
C5AR2 complement component 5a receptor 2
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD34 CD34 molecule
CENPQ centromere protein Q
CFAP44 cilia and flagella associated protein 44
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLIP4 CAP-GLY domain containing linker protein family, member 4
CPNE7 copine VII
CRIP1 cysteine-rich protein 1 (intestinal)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL9 cullin 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DIXDC1 DIX domain containing 1
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FAM63A family with sequence similarity 63, member A
FILIP1L filamin A interacting protein 1-like
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GAREM GRB2 associated, regulator of MAPK1
GFI1 growth factor independent 1 transcription repressor
GLI3 GLI family zinc finger 3
GMPR guanosine monophosphate reductase
GRB7 growth factor receptor-bound protein 7
GRPR gastrin-releasing peptide receptor
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H4A histone cluster 1, H4a
HIST1H4E histone cluster 1, H4e
INO80D INO80 complex subunit D
KPTN kaptin (actin binding protein)
LINC00597 long intergenic non-protein coding RNA 597
LOC390998 ribosomal protein L10 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBIP MAP3K12 binding inhibitory protein 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MORC3 MORC family CW-type zinc finger 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL41 mitochondrial ribosomal protein L41
NEK11 NIMA-related kinase 11
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5E 5'-nucleotidase, ecto (CD73)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARG poly (ADP-ribose) glycohydrolase
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITX2 paired-like homeodomain 2
PLD2 phospholipase D2
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRODH proline dehydrogenase (oxidase) 1
PSD4 pleckstrin and Sec7 domain containing 4
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A4 S100 calcium binding protein A4
SAYSD1 SAYSVFN motif domain containing 1
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SNTA1 syntrophin, alpha 1
SRD5A3 steroid 5 alpha-reductase 3
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TFF2 trefoil factor 2
TGFBR1 transforming growth factor, beta receptor 1
TIGD6 tigger transposable element derived 6
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TMEM183A transmembrane protein 183A
TPCN1 two pore segment channel 1
TRIM21 tripartite motif containing 21
TRIM45 tripartite motif containing 45
TRIM66 tripartite motif containing 66
TTLL1 tubulin tyrosine ligase-like family member 1
USP20 ubiquitin specific peptidase 20
WDR25 WD repeat domain 25
XDH xanthine dehydrogenase
ZBTB22 zinc finger and BTB domain containing 22
ZNF484 zinc finger protein 484
ZNF492 zinc finger protein 492
ZNF574 zinc finger protein 574
ZNF750 zinc finger protein 750