tet2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description tet methylcytosine dioxygenase 2|The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 54790)
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Genes

23 genes co-occuring with the biological term tet2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ASXL1 additional sex combs like transcriptional regulator 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CXXC4 CXXC finger protein 4
DLK1 delta-like 1 homolog (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EBF1 early B-cell factor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FLT3 fms-related tyrosine kinase 3
GATA2 GATA binding protein 2
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IL1B interleukin 1, beta
JAK2 Janus kinase 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
RHOA ras homolog family member A
RUNX1 runt-related transcription factor 1
SRSF2 serine/arginine-rich splicing factor 2
TET1 tet methylcytosine dioxygenase 1
TET2 tet methylcytosine dioxygenase 2
TET3 tet methylcytosine dioxygenase 3