| Dataset | HPO Gene-Disease Associations |
| Category | disease or phenotype associations |
| Type | phenotype |
| Description | During normal embryological development, the spinal cord first occupies the entire length of the vertebral column but goes on to assume a position at the level of L1 due to differential growth of the conus medullaris and the vertebral column. The filum terminale is a slender, threadlike structure that remains after the normal regression of the distal embryonic spinal cord and attaches the spinal cord to the coccyx. A tethered cord results if there is a thickened rope-like filum terminale which anchors the cord at the level of L2 or below, potentially causing neurologic signs owing to abnormal tension on the spinal cord. (Human Phenotype Ontology, HP_0002144) |
| External Link | http://compbio.charite.de/hpoweb/showterm?id=HP:0002144 |
| Similar Terms | |
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4 genes associated with the tethered cord phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
