| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tetracaine-1739 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AMT | aminomethyltransferase |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ASPH | aspartate beta-hydroxylase |
| ATP5SL | ATP5S-like |
| ATXN2 | ataxin 2 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCDC64 | coiled-coil domain containing 64 |
| CCS | copper chaperone for superoxide dismutase |
| CD101 | CD101 molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CEP152 | centrosomal protein 152kDa |
| CKLF | chemokine-like factor |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| COL5A3 | collagen, type V, alpha 3 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) |
| DXO | decapping exoribonuclease |
| EMP2 | epithelial membrane protein 2 |
| ENG | endoglin |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERCC8 | excision repair cross-complementation group 8 |
| FAM134B | family with sequence similarity 134, member B |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FANCF | Fanconi anemia, complementation group F |
| FBLN1 | fibulin 1 |
| FH | fumarate hydratase |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GLRA2 | glycine receptor, alpha 2 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GTSE1 | G-2 and S-phase expressed 1 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HDAC5 | histone deacetylase 5 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL11 | interleukin 11 |
| KLF6 | Kruppel-like factor 6 |
| KYNU | kynureninase |
| LRRC41 | leucine rich repeat containing 41 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LY9 | lymphocyte antigen 9 |
| METAP2 | methionyl aminopeptidase 2 |
| MORC2 | MORC family CW-type zinc finger 2 |
| MPPE1 | metallophosphoesterase 1 |
| MST1 | macrophage stimulating 1 |
| MVK | mevalonate kinase |
| MYL10 | myosin, light chain 10, regulatory |
| NOL12 | nucleolar protein 12 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NUP205 | nucleoporin 205kDa |
| OPA1 | optic atrophy 1 (autosomal dominant) |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PLCG1 | phospholipase C, gamma 1 |
| PLS1 | plastin 1 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) |
| RANBP2 | RAN binding protein 2 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOQ | ras homolog family member Q |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RUNDC3A | RUN domain containing 3A |
| RWDD3 | RWD domain containing 3 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SALL2 | spalt-like transcription factor 2 |
| SCAF4 | SR-related CTD-associated factor 4 |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SH2D2A | SH2 domain containing 2A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNGR2 | synaptogyrin 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM127 | transmembrane protein 127 |
| TMEM186 | transmembrane protein 186 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPSG1 | tryptase gamma 1 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TRIB2 | tribbles pseudokinase 2 |
| UBL3 | ubiquitin-like 3 |
| WDR77 | WD repeat domain 77 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YLPM1 | YLP motif containing 1 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABT1 | activator of basal transcription 1 |
| ARMC7 | armadillo repeat containing 7 |
| ATG4A | autophagy related 4A, cysteine peptidase |
| ATP5G1 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AXIN1 | axin 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL7C | B-cell CLL/lymphoma 7C |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CDK9 | cyclin-dependent kinase 9 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEP131 | centrosomal protein 131kDa |
| CFL1 | cofilin 1 (non-muscle) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CTSD | cathepsin D |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DENND2D | DENN/MADD domain containing 2D |
| DERL2 | derlin 2 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DPP3 | dipeptidyl-peptidase 3 |
| FAM188A | family with sequence similarity 188, member A |
| FAM189B | family with sequence similarity 189, member B |
| FCHO1 | FCH domain only 1 |
| FGL1 | fibrinogen-like 1 |
| FOXK2 | forkhead box K2 |
| FPGS | folylpolyglutamate synthase |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GALR3 | galanin receptor 3 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GIN1 | gypsy retrotransposon integrase 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPX2 | glutathione peroxidase 2 |
| HP | haptoglobin |
| IL2RB | interleukin 2 receptor, beta |
| IRF7 | interferon regulatory factor 7 |
| KRBOX4 | KRAB box domain containing 4 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LIMD2 | LIM domain containing 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSP1 | lymphocyte-specific protein 1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MISP | mitotic spindle positioning |
| MPST | mercaptopyruvate sulfurtransferase |
| MT3 | metallothionein 3 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MTMR12 | myotubularin related protein 12 |
| NDNF | neuron-derived neurotrophic factor |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NECAP2 | NECAP endocytosis associated 2 |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCTP | phosphatidylcholine transfer protein |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PISD | phosphatidylserine decarboxylase |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PORCN | porcupine homolog (Drosophila) |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| QPRT | quinolinate phosphoribosyltransferase |
| RABEPK | Rab9 effector protein with kelch motifs |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RTFDC1 | replication termination factor 2 domain containing 1 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A4RG | SLC2A4 regulator |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC38A6 | solute carrier family 38, member 6 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STAC | SH3 and cysteine rich domain |
| TRIM9 | tripartite motif containing 9 |
| TSPAN32 | tetraspanin 32 |
| TSPYL2 | TSPY-like 2 |
| WDR45 | WD repeat domain 45 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF189 | zinc finger protein 189 |
| ZNF211 | zinc finger protein 211 |
| ZNF223 | zinc finger protein 223 |
| ZNF232 | zinc finger protein 232 |
