| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tetracaine-2888 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD4 | ATP-binding cassette, sub-family D (ALD), member 4 |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| AMACR | alpha-methylacyl-CoA racemase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BLNK | B-cell linker |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD96 | CD96 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CORO1B | coronin, actin binding protein, 1B |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DOCK10 | dedicator of cytokinesis 10 |
| DST | dystonin |
| DTNB | dystrobrevin, beta |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ENO3 | enolase 3 (beta, muscle) |
| FAM105A | family with sequence similarity 105, member A |
| FAM155A | family with sequence similarity 155, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FLJ22184 | |
| FOXI1 | forkhead box I1 |
| FRMD4A | FERM domain containing 4A |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITM2C | integral membrane protein 2C |
| KIAA0319L | KIAA0319-like |
| LHX1 | LIM homeobox 1 |
| LMNA | lamin A/C |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LTB4R | leukotriene B4 receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAL | mal, T-cell differentiation protein |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYOF | myoferlin |
| NDRG1 | N-myc downstream regulated 1 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRTN | neurturin |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP88 | nucleoporin 88kDa |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PENK | proenkephalin |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLK3 | polo-like kinase 3 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRAMEF11 | PRAME family member 11 |
| PSCA | prostate stem cell antigen |
| RAP2B | RAP2B, member of RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHOH | ras homolog family member H |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RTN2 | reticulon 2 |
| S100A8 | S100 calcium binding protein A8 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SC5D | sterol-C5-desaturase |
| SDC2 | syndecan 2 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLN | sarcolipin |
| SRCAP | Snf2-related CREBBP activator protein |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STAB1 | stabilin 1 |
| STIM1 | stromal interaction molecule 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAOK2 | TAO kinase 2 |
| TGFB2 | transforming growth factor, beta 2 |
| THBS3 | thrombospondin 3 |
| TMEM63A | transmembrane protein 63A |
| TPMT | thiopurine S-methyltransferase |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTYH1 | tweety family member 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VAMP5 | vesicle-associated membrane protein 5 |
| WDR61 | WD repeat domain 61 |
| XYLB | xylulokinase homolog (H. influenzae) |
| YOD1 | YOD1 deubiquitinase |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF419 | zinc finger protein 419 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| AMT | aminomethyltransferase |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CFAP70 | cilia and flagella associated protein 70 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORO7 | coronin 7 |
| CXXC4 | CXXC finger protein 4 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDAR | ectodysplasin A receptor |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EXOC6B | exocyst complex component 6B |
| FAM53B | family with sequence similarity 53, member B |
| FAM76A | family with sequence similarity 76, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| GK2 | glycerol kinase 2 |
| GPATCH3 | G patch domain containing 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXC4 | homeobox C4 |
| IFT54 | intraflagellar transport 54 |
| IL22 | interleukin 22 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT13 | keratin 13, type I |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MMD | monocyte to macrophage differentiation-associated |
| MMRN2 | multimerin 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MVP | major vault protein |
| MYOZ3 | myozenin 3 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NME5 | NME/NM23 family member 5 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLM | polymerase (DNA directed), mu |
| PORCN | porcupine homolog (Drosophila) |
| PRR14L | proline rich 14-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS16 | protease, serine, 16 (thymus) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RETN | resistin |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL10L | ribosomal protein L10-like |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SECTM1 | secreted and transmembrane 1 |
| SETD1A | SET domain containing 1A |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| TAOK1 | TAO kinase 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TFF2 | trefoil factor 2 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TH | tyrosine hydroxylase |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TNS2 | tensin 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UPP1 | uridine phosphorylase 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VEGFC | vascular endothelial growth factor C |
| WDR76 | WD repeat domain 76 |
| XAB2 | XPA binding protein 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YY2 | YY2 transcription factor |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
