| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the tetracaine-7473 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AFF2 | AF4/FMR2 family, member 2 |
| AIM1L | absent in melanoma 1-like |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APOC1 | apolipoprotein C-I |
| AR | androgen receptor |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARTN | artemin |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BTG2 | BTG family, member 2 |
| CD83 | CD83 molecule |
| CDK12 | cyclin-dependent kinase 12 |
| CLCA1 | chloride channel accessory 1 |
| CTAGE5 | CTAGE family, member 5 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DCT | dopachrome tautomerase |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DST | dystonin |
| EBF2 | early B-cell factor 2 |
| EFNB3 | ephrin-B3 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FGF13 | fibroblast growth factor 13 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FGL1 | fibrinogen-like 1 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GIPR | gastric inhibitory polypeptide receptor |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| HFE | hemochromatosis |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFNA14 | interferon, alpha 14 |
| IL6R | interleukin 6 receptor |
| INHBC | inhibin, beta C |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| KRT8 | keratin 8, type II |
| LEPROT | leptin receptor overlapping transcript |
| LYRM9 | LYR motif containing 9 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MEF2D | myocyte enhancer factor 2D |
| MID1 | midline 1 |
| MIIP | migration and invasion inhibitory protein |
| MXD4 | MAX dimerization protein 4 |
| MYL5 | myosin, light chain 5, regulatory |
| NAAA | N-acylethanolamine acid amidase |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOX1 | NADPH oxidase 1 |
| NREP | neuronal regeneration related protein |
| NRSN2 | neurensin 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PALM | paralemmin |
| PAX5 | paired box 5 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHA9 | protocadherin alpha 9 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PLCH1 | phospholipase C, eta 1 |
| PLTP | phospholipid transfer protein |
| PODNL1 | podocan-like 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PXDC1 | PX domain containing 1 |
| RECQL5 | RecQ protein-like 5 |
| RPH3A | rabphilin 3A |
| RREB1 | ras responsive element binding protein 1 |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SLAMF7 | SLAM family member 7 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SPRR1A | small proline-rich protein 1A |
| SUGP1 | SURP and G patch domain containing 1 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTC9 | tetratricopeptide repeat domain 9 |
| USP2 | ubiquitin specific peptidase 2 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFX | zinc finger protein, X-linked |
| ZNF747 | zinc finger protein 747 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| ADCY6 | adenylate cyclase 6 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BAGE | B melanoma antigen |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CORO2A | coronin, actin binding protein, 2A |
| CRYL1 | crystallin, lambda 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DIXDC1 | DIX domain containing 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| EAF2 | ELL associated factor 2 |
| EVPL | envoplakin |
| FANCC | Fanconi anemia, complementation group C |
| FKBP5 | FK506 binding protein 5 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FUZ | fuzzy planar cell polarity protein |
| GAB2 | GRB2-associated binding protein 2 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GLCE | glucuronic acid epimerase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR27 | G protein-coupled receptor 27 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BH | histone cluster 1, H2bh |
| HIST1H4F | histone cluster 1, H4f |
| HOXA5 | homeobox A5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTRA1 | HtrA serine peptidase 1 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRF7 | interferon regulatory factor 7 |
| JRKL | JRK-like |
| KLHL36 | kelch-like family member 36 |
| KRT13 | keratin 13, type I |
| LAMB2 | laminin, beta 2 (laminin S) |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHX1 | LIM homeobox 1 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNB2 | lamin B2 |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MB | myoglobin |
| MCOLN3 | mucolipin 3 |
| NBEAL2 | neurobeachin-like 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NLRX1 | NLR family member X1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCDHB3 | protocadherin beta 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROCR | protein C receptor, endothelial |
| PRSS22 | protease, serine, 22 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RECQL4 | RecQ protein-like 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM254 | transmembrane protein 254 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRABD | TraB domain containing |
| TSPYL2 | TSPY-like 2 |
| TTC17 | tetratricopeptide repeat domain 17 |
| UBXN6 | UBX domain protein 6 |
| UFSP2 | UFM1-specific peptidase 2 |
| ULBP2 | UL16 binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF32 | zinc finger protein 32 |
| ZNF586 | zinc finger protein 586 |
| ZNF701 | zinc finger protein 701 |
| ZNF768 | zinc finger protein 768 |