| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the tetracycline-6233 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAM7 | ADAM metallopeptidase domain 7 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATM | ATM serine/threonine kinase |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTD | biotinidase |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COPS7B | COP9 signalosome subunit 7B |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUL4B | cullin 4B |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ECE1 | endothelin converting enzyme 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GAMT | guanidinoacetate N-methyltransferase |
| GANAB | glucosidase, alpha; neutral AB |
| GAS7 | growth arrest-specific 7 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| IFT27 | intraflagellar transport 27 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IRF6 | interferon regulatory factor 6 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLF9 | Kruppel-like factor 9 |
| LEPR | leptin receptor |
| LMBR1L | limb development membrane protein 1-like |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAP4 | microtubule-associated protein 4 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MED1 | mediator complex subunit 1 |
| MLF1 | myeloid leukemia factor 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NDRG2 | NDRG family member 2 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NEK1 | NIMA-related kinase 1 |
| NEK11 | NIMA-related kinase 11 |
| NFRKB | nuclear factor related to kappaB binding protein |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OSMR | oncostatin M receptor |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDS5B | PDS5 cohesin associated factor B |
| PLCH1 | phospholipase C, eta 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRMT2 | protein arginine methyltransferase 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFX7 | regulatory factor X, 7 |
| RIN1 | Ras and Rab interactor 1 |
| RNF122 | ring finger protein 122 |
| RNF39 | ring finger protein 39 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAPCD1 | suppressor APC domain containing 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNGR1 | synaptogyrin 1 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TMEM63A | transmembrane protein 63A |
| TRAV8-3 | T cell receptor alpha variable 8-3 |
| TRIM62 | tripartite motif containing 62 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VAX2 | ventral anterior homeobox 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF468 | zinc finger protein 468 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKRD36 | ankyrin repeat domain 36 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| BAX | BCL2-associated X protein |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CCDC186 | coiled-coil domain containing 186 |
| CD302 | CD302 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP131 | centrosomal protein 131kDa |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CUL9 | cullin 9 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DSPP | dentin sialophosphoprotein |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| ERCC5 | excision repair cross-complementation group 5 |
| EVPL | envoplakin |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FCHO1 | FCH domain only 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT4 | fms-related tyrosine kinase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAN | gigaxonin |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR19 | G protein-coupled receptor 19 |
| HIST1H2BC | histone cluster 1, H2bc |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC10 | homeobox C10 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| INO80D | INO80 complex subunit D |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIZ | kizuna centrosomal protein |
| KLHL21 | kelch-like family member 21 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC730101 | uncharacterized LOC730101 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MICALL2 | MICAL-like 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTMR12 | myotubularin related protein 12 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO1E | myosin IE |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| ONECUT2 | one cut homeobox 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLD2 | phospholipase D2 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCOR3 | REST corepressor 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A4 | S100 calcium binding protein A4 |
| SIRAL2 | SIR2 antiphage like 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TEAD3 | TEA domain family member 3 |
| THBS3 | thrombospondin 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM159 | transmembrane protein 159 |
| TMEM180 | transmembrane protein 180 |
| TMEM184B | transmembrane protein 184B |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPAN15 | tetraspanin 15 |
| TSPAN5 | tetraspanin 5 |
| TUBA3D | tubulin, alpha 3d |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UPK3B | uroplakin 3B |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF205 | zinc finger protein 205 |
| ZNF573 | zinc finger protein 573 |
| ZNF574 | zinc finger protein 574 |
| ZNF586 | zinc finger protein 586 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |