| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tetraethylenepentamine-406 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ANKRD26 | ankyrin repeat domain 26 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| AVEN | apoptosis, caspase activation inhibitor |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCND2 | cyclin D2 |
| CDC25C | cell division cycle 25C |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC1A | C-type lectin domain family 1, member A |
| CPOX | coproporphyrinogen oxidase |
| CST6 | cystatin E/M |
| CTAGE9 | CTAGE family, member 9 |
| DAXX | death-domain associated protein |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DENND3 | DENN/MADD domain containing 3 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIO2 | deiodinase, iodothyronine, type II |
| ECE1 | endothelin converting enzyme 1 |
| EFNB3 | ephrin-B3 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM153A | family with sequence similarity 153, member A |
| FAM76A | family with sequence similarity 76, member A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGL1 | fibrinogen-like 1 |
| FNBP1L | formin binding protein 1-like |
| FOSL1 | FOS-like antigen 1 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAS7 | growth arrest-specific 7 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2I | general transcription factor IIi |
| H2AFY2 | H2A histone family, member Y2 |
| HDAC2 | histone deacetylase 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2RA | interleukin 2 receptor, alpha |
| ITGB5 | integrin, beta 5 |
| JOSD1 | Josephin domain containing 1 |
| KIFC1 | kinesin family member C1 |
| KLHL3 | kelch-like family member 3 |
| LMBR1L | limb development membrane protein 1-like |
| LPIN2 | lipin 2 |
| LY86 | lymphocyte antigen 86 |
| MED14 | mediator complex subunit 14 |
| MED7 | mediator complex subunit 7 |
| MRPS15 | mitochondrial ribosomal protein S15 |
| MTMR3 | myotubularin related protein 3 |
| MVB12B | multivesicular body subunit 12B |
| MYL10 | myosin, light chain 10, regulatory |
| MYO7B | myosin VIIB |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NELL2 | NEL-like 2 (chicken) |
| NPAT | nuclear protein, ataxia-telangiectasia locus |
| NREP | neuronal regeneration related protein |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OCA2 | oculocutaneous albinism II |
| ORC5 | origin recognition complex, subunit 5 |
| PCM1 | pericentriolar material 1 |
| PDCD2 | programmed cell death 2 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLA2G10 | phospholipase A2, group X |
| PLA2G12A | phospholipase A2, group XIIA |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRPF31 | pre-mRNA processing factor 31 |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| PVR | poliovirus receptor |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RBM5 | RNA binding motif protein 5 |
| RPLP2 | ribosomal protein, large, P2 |
| RUNDC3A | RUN domain containing 3A |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SRPK2 | SRSF protein kinase 2 |
| STK19 | serine/threonine kinase 19 |
| T | T, brachyury homolog (mouse) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM87A | transmembrane protein 87A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSPAN3 | tetraspanin 3 |
| TTI1 | TELO2 interacting protein 1 |
| UBE3A | ubiquitin protein ligase E3A |
| UBL3 | ubiquitin-like 3 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| Symbol | Name |
|---|---|
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ATXN2 | ataxin 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA9 | carbonic anhydrase IX |
| CCDC71 | coiled-coil domain containing 71 |
| CD177 | CD177 molecule |
| CD82 | CD82 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CLPS | colipase, pancreatic |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPTP | ceramide-1-phosphate transfer protein |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTRB2 | chymotrypsinogen B2 |
| CTSG | cathepsin G |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DLK2 | delta-like 2 homolog (Drosophila) |
| ELMO3 | engulfment and cell motility 3 |
| EVPL | envoplakin |
| GDAP1L1 | ganglioside induced differentiation associated protein 1-like 1 |
| GLMN | glomulin, FKBP associated protein |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HMGA2 | high mobility group AT-hook 2 |
| HOXC5 | homeobox C5 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL36RN | interleukin 36 receptor antagonist |
| IL4R | interleukin 4 receptor |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF8 | interferon regulatory factor 8 |
| JMJD4 | jumonji domain containing 4 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LENEP | lens epithelial protein |
| LGMN | legumain |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOXL1 | lysyl oxidase-like 1 |
| LRRC20 | leucine rich repeat containing 20 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NAV2 | neuron navigator 2 |
| NCKAP1L | NCK-associated protein 1-like |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NXPH4 | neurexophilin 4 |
| ONECUT2 | one cut homeobox 2 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PCDHB6 | protocadherin beta 6 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLA2G15 | phospholipase A2, group XV |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| PLXNB3 | plexin B3 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRAME | preferentially expressed antigen in melanoma |
| PRDM14 | PR domain containing 14 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing |
| S100A1 | S100 calcium binding protein A1 |
| SAMHD1 | SAM domain and HD domain 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SERTAD3 | SERTA domain containing 3 |
| SH3BP1 | SH3-domain binding protein 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SPAG4 | sperm associated antigen 4 |
| STAG3 | stromal antigen 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNGR4 | synaptogyrin 4 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TMED1 | transmembrane emp24 protein transport domain containing 1 |
| TMEM35 | transmembrane protein 35 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| WNT2 | wingless-type MMTV integration site family member 2 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZNRF4 | zinc and ring finger 4 |