tetraethylenepentamine-412 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tetraethylenepentamine-412 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGRN agrin
AKAP13 A kinase (PRKA) anchor protein 13
AMN amnion associated transmembrane protein
AP3D1 adaptor-related protein complex 3, delta 1 subunit
ATG13 autophagy related 13
AXIN1 axin 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BATF basic leucine zipper transcription factor, ATF-like
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C10ORF76 chromosome 10 open reading frame 76
C11ORF48
C2CD2L C2CD2-like
CANT1 calcium activated nucleotidase 1
CCL19 chemokine (C-C motif) ligand 19
CD1A CD1a molecule
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHD9 chromodomain helicase DNA binding protein 9
CHPF2 chondroitin polymerizing factor 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CTNNBIP1 catenin, beta interacting protein 1
CTRC chymotrypsin C (caldecrin)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DIO2 deiodinase, iodothyronine, type II
DOCK6 dedicator of cytokinesis 6
DSCC1 DNA replication and sister chromatid cohesion 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFCAB1 EF-hand calcium binding domain 1
EMC1 ER membrane protein complex subunit 1
ENG endoglin
EXOC7 exocyst complex component 7
FAM107A family with sequence similarity 107, member A
FEM1B fem-1 homolog b (C. elegans)
FN1 fibronectin 1
GADD45B growth arrest and DNA-damage-inducible, beta
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GM2A GM2 ganglioside activator
GSK3A glycogen synthase kinase 3 alpha
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HTRA2 HtrA serine peptidase 2
IFITM3 interferon induced transmembrane protein 3
IGFBP7 insulin-like growth factor binding protein 7
ING4 inhibitor of growth family, member 4
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITSN2 intersectin 2
JOSD1 Josephin domain containing 1
JRK Jrk homolog (mouse)
JUP junction plakoglobin
KRT17 keratin 17, type I
LRRN2 leucine rich repeat neuronal 2
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MED1 mediator complex subunit 1
MEGF9 multiple EGF-like-domains 9
MFSD12 major facilitator superfamily domain containing 12
MPPE1 metallophosphoesterase 1
NPEPL1 aminopeptidase-like 1
NXF2 nuclear RNA export factor 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAQR6 progestin and adipoQ receptor family member VI
PCGF1 polycomb group ring finger 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEX10 peroxisomal biogenesis factor 10
PEX14 peroxisomal biogenesis factor 14
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PICK1 protein interacting with PRKCA 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLEC plectin
POMT1 protein-O-mannosyltransferase 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
QTRT1 queuine tRNA-ribosyltransferase 1
RALBP1 ralA binding protein 1
RANBP10 RAN binding protein 10
RASA3 RAS p21 protein activator 3
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RECQL5 RecQ protein-like 5
SAFB2 scaffold attachment factor B2
SDHAF1 succinate dehydrogenase complex assembly factor 1
SFSWAP splicing factor, suppressor of white-apricot family
SGSM3 small G protein signaling modulator 3
SIN3B SIN3 transcription regulator family member B
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SVIL supervillin
TGM3 transglutaminase 3
TMEM184B transmembrane protein 184B
TMEM63A transmembrane protein 63A
TMSB4Y thymosin beta 4, Y-linked
TREX1 three prime repair exonuclease 1
VAC14 Vac14 homolog (S. cerevisiae)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WNT10B wingless-type MMTV integration site family, member 10B
ZNF518A zinc finger protein 518A
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
ALDOC aldolase C, fructose-bisphosphate
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BTBD1 BTB (POZ) domain containing 1
C11ORF71 chromosome 11 open reading frame 71
C5ORF30 chromosome 5 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
C8ORF60 chromosome 8 open reading frame 60
CA14 carbonic anhydrase XIV
CAMKV CaM kinase-like vesicle-associated
CD302 CD302 molecule
CD5 CD5 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLEC1A C-type lectin domain family 1, member A
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTN1 contactin 1
CPA4 carboxypeptidase A4
CST8 cystatin 8 (cystatin-related epididymal specific)
CTSE cathepsin E
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DGAT1 diacylglycerol O-acyltransferase 1
DIXDC1 DIX domain containing 1
DOC2A double C2-like domains, alpha
ECE2 endothelin converting enzyme 2
ELAVL4 ELAV like neuron-specific RNA binding protein 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPM2AIP1 EPM2A (laforin) interacting protein 1
FAM153A family with sequence similarity 153, member A
FAM46C family with sequence similarity 46, member C
FGF4 fibroblast growth factor 4
FGFBP1 fibroblast growth factor binding protein 1
FZD4 frizzled class receptor 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
GRHL2 grainyhead-like 2 (Drosophila)
GUSBP3 glucuronidase, beta pseudogene 3
HOOK2 hook microtubule-tethering protein 2
HTRA1 HtrA serine peptidase 1
IHH indian hedgehog
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LATS1 large tumor suppressor kinase 1
LDOC1 leucine zipper, down-regulated in cancer 1
LEFTY1 left-right determination factor 1
LIN7B lin-7 homolog B (C. elegans)
LRP5L low density lipoprotein receptor-related protein 5-like
MED31 mediator complex subunit 31
MICALL2 MICAL-like 2
MOSPD1 motile sperm domain containing 1
MRPL46 mitochondrial ribosomal protein L46
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MYL12B myosin, light chain 12B, regulatory
OCEL1 occludin/ELL domain containing 1
OCLM oculomedin
OMG oligodendrocyte myelin glycoprotein
OPRK1 opioid receptor, kappa 1
OR2C1 olfactory receptor, family 2, subfamily C, member 1
PADI1 peptidyl arginine deiminase, type I
PADI2 peptidyl arginine deiminase, type II
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDH17 protocadherin 17
PDE8B phosphodiesterase 8B
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIGR polymeric immunoglobulin receptor
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLBD1 phospholipase B domain containing 1
PLEK2 pleckstrin 2
PSG4 pregnancy specific beta-1-glycoprotein 4
PVRIG poliovirus receptor related immunoglobulin domain containing
RASAL1 RAS protein activator like 1 (GAP1 like)
RFPL3 ret finger protein-like 3
RHOH ras homolog family member H
RNF11 ring finger protein 11
RNF39 ring finger protein 39
SALL2 spalt-like transcription factor 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SDHAF3 succinate dehydrogenase complex assembly factor 3
SDS serine dehydratase
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
T T, brachyury homolog (mouse)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFCP2L1 transcription factor CP2-like 1
TG thyroglobulin
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM8B transmembrane protein 8B
TP53I3 tumor protein p53 inducible protein 3
TRAPPC11 trafficking protein particle complex 11
TRIM25 tripartite motif containing 25
VEZT vezatin, adherens junctions transmembrane protein
XYLT1 xylosyltransferase I
ZNF74 zinc finger protein 74
ZNF85 zinc finger protein 85