| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the tetraethylenepentamine-457 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| AREG | amphiregulin |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CBX4 | chromobox homolog 4 |
| CD58 | CD58 molecule |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CDYL | chromodomain protein, Y-like |
| CFAP70 | cilia and flagella associated protein 70 |
| CLU | clusterin |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPE | carboxypeptidase E |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CREBL2 | cAMP responsive element binding protein-like 2 |
| CROT | carnitine O-octanoyltransferase |
| CSRP2 | cysteine and glycine-rich protein 2 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| FAM188A | family with sequence similarity 188, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GAK | cyclin G associated kinase |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GHR | growth hormone receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HADH | hydroxyacyl-CoA dehydrogenase |
| HLA-C | major histocompatibility complex, class I, C |
| HMOX2 | heme oxygenase 2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KIAA0141 | KIAA0141 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NIPAL2 | NIPA-like domain containing 2 |
| NMB | neuromedin B |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| PAK1IP1 | PAK1 interacting protein 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLA2G16 | phospholipase A2, group XVI |
| PRRC2B | proline-rich coiled-coil 2B |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBM25 | RNA binding motif protein 25 |
| RING1 | ring finger protein 1 |
| RPL13 | ribosomal protein L13 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 |
| SPPL2B | signal peptide peptidase like 2B |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRP72 | signal recognition particle 72kDa |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STX2 | syntaxin 2 |
| SURF2 | surfeit 2 |
| SYNGR1 | synaptogyrin 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
| TMC6 | transmembrane channel-like 6 |
| TMEM161A | transmembrane protein 161A |
| TMEM38B | transmembrane protein 38B |
| TMEM8B | transmembrane protein 8B |
| TNS4 | tensin 4 |
| TREX1 | three prime repair exonuclease 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| U2SURP | U2 snRNP-associated SURP domain containing |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VRK3 | vaccinia related kinase 3 |
| WDR13 | WD repeat domain 13 |
| ZFX | zinc finger protein, X-linked |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| ADRA2B | adrenoceptor alpha 2B |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| APCS | amyloid P component, serum |
| APOC4 | apolipoprotein C-IV |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| BDNF | brain-derived neurotrophic factor |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BSPRY | B-box and SPRY domain containing |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCDC176 | coiled-coil domain containing 176 |
| CD83 | CD83 molecule |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLEC1A | C-type lectin domain family 1, member A |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| CTRB2 | chymotrypsinogen B2 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM153A | family with sequence similarity 153, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGL1 | fibrinogen-like 1 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT3 | fms-related tyrosine kinase 3 |
| FMO4 | flavin containing monooxygenase 4 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GALR3 | galanin receptor 3 |
| GK2 | glycerol kinase 2 |
| GLRA2 | glycine receptor, alpha 2 |
| GPATCH3 | G patch domain containing 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GPS1 | G protein pathway suppressor 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| IFT20 | intraflagellar transport 20 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| INO80D | INO80 complex subunit D |
| JAM3 | junctional adhesion molecule 3 |
| KIAA0753 | KIAA0753 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT37 | keratin 37, type I |
| LGALS13 | lectin, galactoside-binding, soluble, 13 |
| LMTK1 | lemur tail kinase 1 |
| LRRC15 | leucine rich repeat containing 15 |
| LY86 | lymphocyte antigen 86 |
| MB | myoglobin |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| NEUROD2 | neuronal differentiation 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| OR2C1 | olfactory receptor, family 2, subfamily C, member 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PF4 | platelet factor 4 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIP | prolactin-induced protein |
| PLCD1 | phospholipase C, delta 1 |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein |
| PRSS23 | protease, serine, 23 |
| PRSS8 | protease, serine, 8 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| QSER1 | glutamine and serine rich 1 |
| R3HDM2 | R3H domain containing 2 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RNF185 | ring finger protein 185 |
| SECTM1 | secreted and transmembrane 1 |
| SEPW1 | selenoprotein W, 1 |
| SERTAD3 | SERTA domain containing 3 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SSUH2 | ssu-2 homolog (C. elegans) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUSD4 | sushi domain containing 4 |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM66 | tripartite motif containing 66 |
| UPK2 | uroplakin 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF175 | zinc finger protein 175 |
| ZNF280A | zinc finger protein 280A |
